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Buspirone Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Buspirone Remove Buspirone from your drug comparison Xanax Remove Xanax from your drug comparison Clonazepam Remove Clonazepam from your drug comparison
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Buspirone Remove Buspirone from your drug comparison Xanax alprazolam Remove Xanax from your drug comparison Clonazepam Remove Clonazepam from your drug comparison

Buspirone may be used for the treatment of anxiety and is less likely to cause sedation than other anti-anxiety drugs. Prescribed for Anxiety, Panic Disorder. May also be prescribed off label for... View more

Xanax may be used for the treatment of anxiety or panic disorder; however, it is addictive and withdrawal symptoms can be severe. Prescribed for Anxiety, Panic Disorder, Depression. Xanax may also be... View more

Clonazepam may reduce seizure frequency in specific seizure disorders and can be used short-term for panic disorder; however, it can cause dependence and withdrawal symptoms on discontinuation.... View more

Prescription only

Prescription only

Prescription only

Ratings & Reviews

View all 1036 reviews

View all 811 reviews

View all 1689 reviews

Drug Class

Side Effects

Commonly reported side effects include: dizziness.

See the full buspirone side effects document.

Common side effects include: ataxia, cognitive dysfunction, constipation, difficulty in micturition, drowsiness, dysarthria, fatigue, memory impairment, skin rash, weight gain, weight loss, anxiety, blurred vision, diarrhea, insomnia, decreased libido, increased appetite, decreased appetite.

See the full Xanax side effects document.

Commonly reported side effects include: drowsiness.

See the full clonazepam side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 100 each
Dosage 10 mg
Per Unit* $0.46 - $0.54
Cost* $45.78 - $54.43

View all buspirone prices

Quantity 10 tablet
Dosage 0.25 mg
Per Unit* $3.81
Cost* $38.07

View all Xanax prices and generic prices

Quantity 10 tablet
Dosage 0.5 mg
Per Unit* $0.52
Cost* $5.15

View all clonazepam prices

Get free Discount Card

Get free Discount Card

Get free Discount Card

Generic Availability

Yes (this medicine)

Yes

Yes (this medicine)

Dosage Form(s) Available
  • Oral tablet
  • Oral tablet
  • Oral tablet
  • Oral tablet, disintegrating

Brand Names
BuSpar Other alprazolam brands include: Alprazolam Intensol, Xanax XR Klonopin

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

11.3 hours

20 hours

40 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
4
Some potential for abuse

Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
4
Some potential for abuse

Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.

Pregnancy Category
B
Category B No proven risk in humans

See the full Pregnancy Warnings document.
D
Category D Positive evidence of risk

See the full Pregnancy Warnings document.
D
Category D Positive evidence of risk

See the full Pregnancy Warnings document.

FDA Alerts

N/A

FDA Alerts (3)

FDA Alerts (1)

Drug Interactions

A total of 430 drugs are known to interact with buspirone:

  • 88 major drug interactions (320 brand and generic names)
  • 340 moderate drug interactions (1262 brand and generic names)
  • 2 minor drug interactions (5 brand and generic names)

A total of 476 drugs are known to interact with Xanax:

  • 35 major drug interactions (168 brand and generic names)
  • 401 moderate drug interactions (1461 brand and generic names)
  • 40 minor drug interactions (330 brand and generic names)

A total of 452 drugs are known to interact with clonazepam:

  • 28 major drug interactions (149 brand and generic names)
  • 392 moderate drug interactions (1451 brand and generic names)
  • 32 minor drug interactions (206 brand and generic names)

Alcohol/Food/Lifestyle Interactions
  • You should avoid the use of alcohol while being treated with busPIRone. Alcohol can increase the... View more
  • Grapefruit and grapefruit juice may interact with ALPRAZolam and lead to potentially dangerous side... View more
  • Using clonazePAM together with alcohol can increase nervous system side effects such as dizziness,... View more

Disease Interactions

First Approval Date

September 29, 1986

October 16, 1981

June 04, 1975

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer