Buspirone Alternatives Compared
| Buspirone | Xanax | Clonazepam |
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| Buspirone | Xanax alprazolam | Clonazepam |
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Buspirone may be used for the treatment of anxiety and is less likely to cause sedation than other anti-anxiety drugs. Prescribed for Anxiety, Panic Disorder. May also be prescribed off label for... View more |
Xanax may be used for the treatment of anxiety or panic disorder; however, it is addictive and withdrawal symptoms can be severe. Prescribed for Anxiety, Panic Disorder. Xanax may also be used for... View more |
Clonazepam may reduce seizure frequency in specific seizure disorders and can be used short-term for panic disorder, to relieve anxiety, or to sedate. When used long-term it can cause dependence and... View more |
Choose a suggestion below Anxiety
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| More about Buspirone | More about Xanax (alprazolam) | More about Clonazepam | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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Prescription only |
Prescription only |
Prescription only |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Buspirone has an average rating of 5.8 out of 10 from a total of 1205 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 37% reported a negative effect. |
Xanax has an average rating of 8.7 out of 10 from a total of 782 ratings on Drugs.com. 83% of reviewers reported a positive effect, while 8% reported a negative effect. |
Clonazepam has an average rating of 8.1 out of 10 from a total of 1893 ratings on Drugs.com. 78% of reviewers reported a positive effect, while 12% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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Commonly reported side effects include: dizziness. See the full buspirone side effects document. |
Common side effects include: ataxia, cognitive dysfunction, constipation, difficulty in micturition, drowsiness, dysarthria, fatigue, memory impairment, skin rash, weight gain, weight loss, anxiety, blurred vision, diarrhea, insomnia, decreased libido, increased appetite, decreased appetite. See the full Xanax side effects document. |
Commonly reported side effects include: drowsiness. See the full clonazepam side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all buspirone prices |
View all Xanax prices and generic prices |
View all clonazepam prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| BuSpar | Other alprazolam brands include: Alprazolam Intensol, Xanax XR | Klonopin | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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11.3 hours |
20 hours |
40 hours |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 465 drugs are known to interact with buspirone:
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A total of 514 drugs are known to interact with Xanax:
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A total of 486 drugs are known to interact with clonazepam:
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| First Approval Date | ||||||||||||||||||||||||||
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September 29, 1986 |
October 16, 1981 |
June 04, 1975 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.