Comparing Bupropion vs Sibutramine
Bupropion | Sibutramine |
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Bupropion | Sibutramine |
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Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Prescription only
Prescribed for Weight Loss (Obesity/Overweight). Sibutramine may also be used for purposes not listed in this medication guide. |
Related suggestions Weight Loss (Obesity/Overweight)
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More about Bupropion | |||||||||
Ratings & Reviews | |||||||||
Bupropion has an average rating of 7.0 out of 10 from a total of 2904 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 20% reported a negative effect. |
Sibutramine has an average rating of 8.5 out of 10 from a total of 93 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 5% reported a negative effect. |
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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Bupropion side effects |
View all Sibutramine side effects |
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Drug Class | |||||||||
Generic Availability | |||||||||
Lower cost generic |
N/A |
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Pricing and Coupons * Prices are without insurance | |||||||||
View all Bupropion prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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Dosage Forms | |||||||||
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N/A |
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Brand Names | |||||||||
Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL |
N/A |
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Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
30 hours |
16 hours |
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CSA Schedule 1 View glossary of CSA terms | |||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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Pregnancy Category | |||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||
A total of 559 drugs are known to interact with Bupropion:
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A total of 588 drugs are known to interact with Sibutramine:
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Alcohol/Food/Lifestyle Interactions | |||||||||
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Disease Interactions | |||||||||
First Approval Date | |||||||||
December 30, 1985 |
N/A |
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WADA Class View classifications | |||||||||
N/A |
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More Information | |||||||||
Patient Resources | |||||||||
N/A |
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Professional Resources | |||||||||
N/A |
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Related Treatment Guide | |||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.