Comparing Bupropion vs Nicotine
| Bupropion | Nicotine |
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| Bupropion | Nicotine |
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Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Prescription and OTC
Prescribed for Smoking Cessation. Nicotine may also be used for purposes not listed in this medication guide. |
Related suggestions Smoking Cessation
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| More about Bupropion | More about Nicotine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Bupropion has an average rating of 7.0 out of 10 from a total of 2904 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 20% reported a negative effect. |
Nicotine has an average rating of 7.6 out of 10 from a total of 202 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 16% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Bupropion side effects |
View all Nicotine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Bupropion prices |
View all Nicotine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | Commit, Habitrol, Leader Nicotine Polacrilex, Nicoderm CQ, Nicorette, Nicorette DS, Nicotrol Inhaler, Nicotrol NS | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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30 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 559 drugs are known to interact with Bupropion:
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A total of 90 drugs are known to interact with Nicotine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 30, 1985 |
January 13, 1984 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.