Comparing Bupropion vs Mirtazapine

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Bupropion	Mirtazapine	Enter another drug to compare

Bupropion

Mirtazapine

Prescription only

Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more

Prescription only

Mirtazapine may be used in the treatment of depression; however, its use may be limited by its prominent sedative effects. Prescribed for Depression, Major Depressive Disorder. May also be prescribed... View more

More about Bupropion

More about Mirtazapine

Generic Status

Lower-cost generic is available

Ratings & Reviews

Bupropion has an average rating of 7.0 out of 10 from a total of 2734 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 21% reported a negative effect.

Mirtazapine has an average rating of 6.7 out of 10 from a total of 1880 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 22% reported a negative effect.

View all 2734 reviews

View all 1880 reviews

Drug Class

Tetracyclic antidepressants

Side Effects

Commonly reported side effects include:

insomnia
nausea
pharyngitis
weight loss
constipation
dizziness
headache
xerostomia

See also: bupropion side effects in more detail.

Commonly reported side effects include:

severe sedation
constipation
drowsiness
increased serum cholesterol
weight gain
fatigue
insomnia
increased appetite
xerostomia
decreased appetite
show all 10

See also: mirtazapine side effects in more detail.

Pricing and Coupons * Prices are without insurance

Quantity	30 each
Dosage	150 mg/24 hours
Per Unit^*	$1.51
Cost^*	$45.27

View all bupropion prices

Quantity	100 each
Dosage	30 mg
Per Unit^*	$0.27 - $0.82
Cost^*	$27.05 - $81.87

View all mirtazapine prices

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Dosage Form(s) Available

Oral tablet
Oral tablet, extended release

Oral tablet
Oral tablet, disintegrating

Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

30 hours

40 hours

CSA Schedule ** View glossary of terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 484 drugs are known to interact with bupropion:

215 major drug interactions (939 brand and generic names)
264 moderate drug interactions (1240 brand and generic names)
5 minor drug interactions (17 brand and generic names)

A total of 623 drugs are known to interact with mirtazapine:

132 major drug interactions (478 brand and generic names)
489 moderate drug interactions (1874 brand and generic names)
2 minor drug interactions (5 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Using buPROPion with alcohol may increase the risk of uncommon side effects such as seizures... View more

Alcohol can increase the nervous system side effects of mirtazapine such as dizziness, drowsiness... View more

Disease Interactions

First Approval Date

December 30, 1985

June 14, 1996

WADA Class View World Anti-Doping Agency classifications.

N/A

More Information

Patient resources

Overview

Professional Resources

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Bupropion vs Mirtazapine

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