Benzonatate Alternatives Compared
| Benzonatate | Mucinex | Benadryl |
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| Benzonatate | Mucinex (guaifenesin) | Benadryl (diphenhydramine) |
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Prescription only
Benzonatate relieves a dry cough; however, the capsules must be swallowed whole because the risk of a fatal overdosage is increased if the capsules are opened in any way. Prescribed for Cough... View more |
Prescription and OTC
Mucinex is an expectorant that helps thin mucus allowing it to be more easily cleared by coughing. Side effects are few; however, anecdotally, sleeplessness may be a problem if Mucinex is taken late... View more |
Prescription and OTC
Benadryl is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, as a sleep aid, and relieve some symptoms of Parkinson's disease. Sedation is a common side effect... View more |
Related suggestions |
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| More about Benzonatate | More about Mucinex (guaifenesin) | More about Benadryl (diphenhydramine) | ||||||||||||||||||||||||
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Benzonatate has an average rating of 3.9 out of 10 from a total of 717 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 64% reported a negative effect. |
Mucinex has an average rating of 6.2 out of 10 from a total of 149 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 34% reported a negative effect. |
Benadryl has an average rating of 7.1 out of 10 from a total of 71 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects | ||||||||||||||||||||||||||
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See also: benzonatate side effects in more detail. |
See also: Mucinex side effects in more detail. |
See also: Benadryl side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all benzonatate prices |
View all Mucinex prices and generic prices |
View all Benadryl prices and generic prices |
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| Brand Names | ||||||||||||||||||||||||||
| Tessalon, Tessalon Perles | Other guaifenesin brands include: Air Power, Allfen Jr, Altarussin, Altorant, Amibid LA, Anti-Tuss, Aquamist, Balminil Expectorant, Beechams Veno's Expectorant, Beechams Veno's for Kids Chesty Cough, Benadryl Chesty Forte, Benylin E, Bidex-400, Breonesin, Bronchoril, Buckley's Chest Congestion, Calmylin Expectorant, Diabetic Expectorant, Diabetic Tuss, Diabetic Tussin Chest Congestion, Diabetic Tussin Mucus Relief, Dristan Chesty Cough, Dristan Chesty Cough Guaiphenesin, Drituss G, Duratuss G, Family Meltus Chesty Coughs, Fenesin, Fenesin IR, Fenex-LA, G Bid, Ganidin NR, Genatuss, GG 200 NR, GG-Cen, Giltuss Children's EX Expectorant, Giltuss EX Expectorant, Glytuss, Gua-SR, Guaiatussin, Guaibid-LA, Guaifen NR, Guaifenesin LA, Guaifenex G, Guaifenex LA, Guiacough, Guiadrine G-1200, Guiatuss, Help I Have Chest Congestion, Hill's Balsam Chesty Cough, Humavent LA, Humibid, Humibid E, Humibid Pediatric, Humigen LA, Hytuss, Junior Meltus Chesty Coughs with Catarrh, Junior Meltus Colour and Sugar Free Expectorant, Lemsip Cough Chesty, Mucaplex, Mucinex Children's Chest Congestion, Mucinex for Kids, Mucinex Maximum Strength, Mucobid-LA, Organ-1 NR, Refenesen Chest Congestion Relief, Robafen, Robitussin Mucus + Chest Congestion, Rompe Pecho EX, Scot-Tussin Expectorant, Siltuss DAS, Siltussin DAS, Siltussin DAS-NA, TabTussin 400, Tussin Expectorant, Tussin Mucus + Chest Congestion, Xpect View more | Other diphenhydramine brands include: Aler-Dryl, Aler-Tab, Aller-G-Time, Allergia-C, Allermax, Altaryl, Banaril, Banophen, Beldin, Belix, Ben-Tann, Benadryl Allergy, Benadryl Children's Allergy, Benahist-10, Benahist-50, Benoject-50, Buckley's Bedtime, Bydramine, Calm-Aid, Complete Allergy Relief, Compoz Nighttime Sleep Aid, ConRx Allergy, Dicopanol, Diphedryl, Diphen, Diphen AF, Diphen Cough, Diphenadryl, Diphendryl, Diphenhist, Diphenmax, Diphenydramine Quick Melt, Diphenyl, Diphenylin, Dormin, DPH, Dytan, Dytuss, Genahist, Help I Can't Sleep, Histaprin, Hydramine, Hydramine Compound, Hydramine Cough Syrup, Hyrexin, Miles Nervine, Nytol, Nytol Caplet, Nytol QuickCaps, Pharbedryl, Scot-Tussin Allergy, Siladryl Allergy, Silphen Cough, Simply Sleep, Sleep Tab II, Sleep-ettes D, Sleepinal, Sleepwell 2-nite, Snooze Fast, Sominex, Sominex Maximum Strength Caplet, Trux-adryl, Twilite, Unisom Liquid, Unisom SleepGels, Unisom SleepMelts, Unisom SleepMinis, Valu-Dryl, Vanamine PD, Vicks QlearQuil Nighttime Allergy Relief, Z-Sleep, ZzzQuil View more | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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N/A |
1 hour |
9.3 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 1 drugs are known to interact with benzonatate:
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No known drug interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
A total of 415 drugs are known to interact with Benadryl:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | ||||||||||||||||||||||||||
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September 24, 2014 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.