Comparing Baclofen vs Tizanidine
| Baclofen | Tizanidine |
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| Baclofen | Tizanidine |
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Prescription only
Baclofen relieves muscle spasms associated with multiple sclerosis and spinal cord injury or disease, but its use is limited by its ability to cause sedation and increase seizure risk. Prescribed for... View more |
Prescription only
Tizanidine relieves muscle spasms but may cause sleepiness, a drop in blood pressure, and sedation. The dosage should be individualized and because it only lasts for a short time in the body, can be... View more |
Related suggestions Muscle Spasm (Involuntary Hypertonicity)
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| More about Baclofen | More about Tizanidine | ||||||||||||||||
| Generic Status | |||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Baclofen has an average rating of 6.9 out of 10 from a total of 412 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 24% reported a negative effect. |
Tizanidine has an average rating of 6.2 out of 10 from a total of 358 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 29% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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Commonly reported side effects include:
See also: baclofen side effects in more detail. |
Commonly reported side effects include:
See also: tizanidine side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all baclofen prices |
View all tizanidine prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Fleqsuvy, Gablofen, Lioresal, Lioresal Intrathecal, Lyvispah, Ozobax | Zanaflex | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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6.8 hours |
2.5 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 358 drugs are known to interact with baclofen:
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A total of 589 drugs are known to interact with tizanidine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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November 22, 1977 |
November 27, 1996 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.