Ativan Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Ativan (lorazepam)	Xanax (alprazolam)	Clonazepam	Enter another drug to compare

Ativan (lorazepam)

Xanax (alprazolam)

Clonazepam

Prescription only

Ativan may be used for the treatment of anxiety or as a preoperative medicine. It is potentially addictive and a withdrawal syndrome may be experienced upon discontinuation. Sedation is a common... View more

Prescription only

Xanax may be used for the treatment of anxiety or panic disorder; however, it is addictive, and withdrawal symptoms can be severe. Can interact with several drugs including those that cause... View more

Prescription only

Clonazepam may reduce seizure frequency in specific seizure disorders and can be used short-term for panic disorder, to relieve anxiety, or to sedate. When used long-term it can cause dependence and... View more

More about Ativan (lorazepam)

More about Xanax (alprazolam)

More about Clonazepam

Ratings & Reviews

Ativan has an average rating of 8.0 out of 10 from a total of 479 ratings on Drugs.com. 74% of reviewers reported a positive effect, while 13% reported a negative effect.

Xanax has an average rating of 8.6 out of 10 from a total of 919 ratings on Drugs.com. 82% of reviewers reported a positive effect, while 8% reported a negative effect.

Clonazepam has an average rating of 8.2 out of 10 from a total of 2180 ratings on Drugs.com. 78% of reviewers reported a positive effect, while 12% reported a negative effect.

View all 479 reviews

View all 919 reviews

View all 2180 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Anxiety (8.1%)
Drowsiness (6.7%)
Withdrawal (5.2%)
Sleepy (4.2%)
Addiction (3.8%)
Dizziness (3.3%)
Insomnia (3.3%)

View all Ativan side effects

Addiction (5.7%)
Anxiety (5.5%)
Withdrawal (5.2%)
Drowsiness (4.6%)
Panic attacks (4.5%)
Insomnia (2.8%)
Tiredness (2.4%)

View all Xanax side effects

Anxiety (7.1%)
Drowsiness (6.7%)
Withdrawal (6.5%)
Insomnia (4.7%)
Tiredness (3.2%)
Depression (3.2%)
Panic attacks (3.1%)

View all Clonazepam side effects

Drug Class

Benzodiazepines

Generic Availability

Lower cost generic approved

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	100 tablet
Strength	1 mg
Per unit^*	$52.85
Cost^*	$5,285.27

View all Ativan prices

Quantity	100 tablet
Strength	0.25 mg
Per unit^*	$6.09
Cost^*	$609.00

View all Xanax prices

Quantity	10 tablet
Strength	0.5 mg
Per unit^*	$1.04 - $1.22
Cost^*	$10.36 - $12.19

View all Clonazepam prices

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Dosage Forms

Injectable solution
Oral tablet

Oral tablet

Oral tablet
Oral tablet, disintegrating

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

25 hours

20 hours

40 hours

CSA Schedule ¹ View glossary of CSA terms

Some potential for abuse

Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.

Some potential for abuse

Pregnancy Category

Category D Positive evidence of risk

See the full pregnancy warnings document.

Category D Positive evidence of risk

See the full pregnancy warnings document.

Category D Positive evidence of risk

See the full pregnancy warnings document.

Drug Interactions

A total of 406 drugs are known to interact with Ativan:

31 major drug interactions (163 brand and generic names)
344 moderate drug interactions (1377 brand and generic names)
31 minor drug interactions (219 brand and generic names)

A total of 562 drugs are known to interact with Xanax:

55 major drug interactions (214 brand and generic names)
467 moderate drug interactions (1725 brand and generic names)
40 minor drug interactions (331 brand and generic names)

A total of 532 drugs are known to interact with Clonazepam:

30 major drug interactions (155 brand and generic names)
469 moderate drug interactions (1736 brand and generic names)
33 minor drug interactions (210 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol can increase the nervous system side effects of LORazepam such as dizziness, drowsiness... View more

Grapefruit and grapefruit juice may interact with ALPRAZolam and lead to potentially dangerous side... View more

Using clonazePAM together with alcohol can increase nervous system side effects such as dizziness... View more

Disease Interactions

First Approval Date

September 30, 1977

N/A

June 04, 1975

WADA Class View classifications

N/A

More Information

Patient Resources

Ativan uses

Xanax uses

Clonazepam uses

Professional Resources

Prescribing information

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Ativan Alternatives Compared

See also:

Lexapro

Zoloft

Ozempic

Xanax

Prozac

Cymbalta

Zofran

Benadryl

Klonopin

Zyprexa

Further information

Ativan Alternatives Compared

See also:

Further information

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