Comparing Amlodipine vs Spironolactone
| Amlodipine | Spironolactone |
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| Amlodipine | Spironolactone |
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Prescription only
Amlodipine is used to lower high blood pressure (hypertension) and to treat treat Coronary Artery Disease (CAD). Edema (swelling around the ankles) is the main side effect. Shortness of breath... View more |
Prescription only
Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. It does not cause potassium loss from the body; however... View more |
Related suggestions High Blood Pressure (Hypertension)
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| More about Amlodipine | More about Spironolactone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Amlodipine has an average rating of 4.4 out of 10 from a total of 846 ratings on Drugs.com. 28% of reviewers reported a positive effect, while 52% reported a negative effect. |
Spironolactone has an average rating of 6.8 out of 10 from a total of 706 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 25% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Amlodipine side effects |
View all Spironolactone side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Amlodipine prices |
View all Spironolactone prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Katerzia, Norliqva, Norvasc, Sdamlo | Aldactone, CaroSpir | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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35 hours |
37 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 546 drugs are known to interact with Amlodipine:
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A total of 388 drugs are known to interact with Spironolactone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 31, 1992 |
January 21, 1960 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.