Alprazolam Alternatives Compared
| Alprazolam | Rexulti (brexpiprazole) | Bupropion |
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| Alprazolam | Rexulti (brexpiprazole) | Bupropion |
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Prescription only
Alprazolam effectively relieves anxiety; however, it is addictive, and withdrawal symptoms can be severe. Other common side effects include low blood pressure, dizziness on standing (which may... View more |
Prescription only
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression, or used to relieve agitation associated with dementia in Alzheimer's disease. Most people... View more |
Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Related suggestions |
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| More about Alprazolam | More about Rexulti (brexpiprazole) | More about Bupropion | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Alprazolam has an average rating of 8.6 out of 10 from a total of 1495 ratings on Drugs.com. 83% of reviewers reported a positive effect, while 8% reported a negative effect. |
Rexulti has an average rating of 6.6 out of 10 from a total of 499 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 25% reported a negative effect. |
Bupropion has an average rating of 7.0 out of 10 from a total of 2913 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Alprazolam side effects |
View all Rexulti side effects |
View all Bupropion side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Alprazolam prices |
View all Rexulti prices |
View all Bupropion prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Alprazolam Intensol, Xanax, Xanax XR |
N/A |
Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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20 hours |
91 hours |
30 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 563 drugs are known to interact with Alprazolam:
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A total of 601 drugs are known to interact with Rexulti:
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A total of 560 drugs are known to interact with Bupropion:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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October 16, 1981 |
July 10, 2015 |
December 30, 1985 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.