5-hydroxytryptophan Alternatives Compared
| 5-hydroxytryptophan | Bupropion | Sertraline |
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| 5-hydroxytryptophan | Bupropion | Sertraline |
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Over-the-counter
Used for ADHD, Anxiety, Insomnia, Headache, Depression, Fibromyalgia. 5-hydroxytryptophan may also be used for purposes not listed in this medication guide. |
Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Prescription only
Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Headaches, nausea, diarrhea, weight loss, insomnia, tremors, and sexual dysfunction are the... View more |
Related suggestions Depression
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| More about 5-hydroxytryptophan | More about Bupropion | More about Sertraline | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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5-hydroxytryptophan has an average rating of 6.5 out of 10 from a total of 191 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 26% reported a negative effect. |
Bupropion has an average rating of 7.0 out of 10 from a total of 2910 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 20% reported a negative effect. |
Sertraline has an average rating of 7.3 out of 10 from a total of 4580 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
View all 5-hydroxytryptophan side effects |
View all Bupropion side effects |
View all Sertraline side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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N/A |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Bupropion prices |
View all Sertraline prices |
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| Dosage Forms | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
| 5-HTP | Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | Zoloft | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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4 hours |
30 hours |
66 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category N
Not classified
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 101 drugs are known to interact with 5-hydroxytryptophan:
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A total of 559 drugs are known to interact with Bupropion:
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A total of 673 drugs are known to interact with Sertraline:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | ||||||||||||||||||
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N/A |
December 30, 1985 |
December 30, 1991 |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient Resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
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N/A |
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| Related Treatment Guide | ||||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.