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Zometa and Tiredness: What Users Say

Tiredness: mentioned by 5 users (11.4%)

Based on user experiences from 44 Zometa reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

chills 22.7%
pain 22.7%
fever 15.9%
flu-like symptoms 13.6%
joint pain 13.6%
body aches 11.4%
bone pain 11.4%
headaches 11.4%
tiredness 11.4%
back pain 9.1%

Reviews for Zometa

  • jak...
  • Taken for less than 1 month
  • June 6, 2019

For Osteoporosis "For four weeks, I had little to no appetite and periods of tiredness. For the first 3 weeks, I was also in a stupor, tired, and weak every day, with nausea daily. Along with these symptoms, for the first 2 weeks, I had on and off fever, chills, headache, no energy, sweats at night. I felt like I was drugged and was weak, unstable, and sick. I would never, never take Zometa again, and I do NOT recommend it."

2 / 10
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  • jak...
  • Taken for less than 1 month
  • June 6, 2019

For Osteoporosis "For four weeks, I had little to no appetite and periods of tiredness. For the first 3 weeks, I was also in a stupor, tired, and weak every day, with nausea daily. Along with these symptoms, for the first 2 weeks, I had on and off fever, chills, headache, no energy, sweats at night. I felt like I was drugged and was weak, unstable, and sick. I would never, never take Zometa again, and I do NOT recommend it."

2 / 10
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115 Report
  • Blu...
  • Taken for 1 to 6 months
  • February 28, 2020

For Hypercalcemia of Malignancy "My oncologist ordered this as a bone treatment. I was doing just fine without it. Now my legs are in pain, and I'm tired most of the time. I will NEVER take this crap again. It's a typical poison that America's corrupt pharmaceutical industry pushes on people. There are other, safer ways to get your damaged bones to absorb calcium. I have nothing but the most profound contempt for the makers of this product."

1 / 10
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72 Report

Frequently asked questions

  • Jms...
  • Taken for 6 months to 1 year
  • April 6, 2022

For Hypercalcemia of Malignancy "I agree with other reviewers, you will experience all side effects listed. I have had 7 infusions (1 monthly) for 1 year. After infusion, I’m fine for a day. Usually, 1-2 weeks after, I will be extremely tired, with bloating and burning skin on abdomen. Side effects vary monthly."

2 / 10
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  • ros...
  • Taken for 1 to 6 months
  • April 24, 2025

"I have taken Zometa infusions for 7 months. I was extremely tired to the point I didn't want to get out of bed, sleeping more than I ever had, only being awake at most 5 hours a day, lost my appetite, lost weight, muscle pain, and just quality of life was so that I didn't want to go anywhere or do anything. I have not done infusions since January because I was having issues with my mouth. Hurt to wear my partial. After reading about the downside of Zometa, I do not want to continue taking it. Going to ask my doctor for a different treatment. I have also noticed after not taking the infusions, I sleep less, awake, and feel so much better. Was getting 4 mg once a month. This drug scares me."

5 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.