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Zometa and Body Aches: What Users Say

Body aches: mentioned by 6 users (13.3%)

Based on user experiences from 45 Zometa reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

chills 24.4%
pain 22.2%
fever 15.6%
body aches 13.3%
flu-like symptoms 13.3%
headaches 13.3%
joint pain 13.3%
bone pain 11.1%
tiredness 11.1%
back pain 8.9%

Reviews for Zometa

Commonly mentioned side effects
  • Anonymous
  • Taken for less than 1 month
  • February 11, 2021

For Osteoporosis "Wonderful!! If you want to say farewell to your already healthy and happy life for months, even for years, take this rubbish, even one dose! You will get paralyzed and achy for so long! DO NOT try this junk, or you will wish for death rather than taking the side effects! Beware! You will experience all the listed side effects! Long-lasting and disastrous! Make your choice!"

1 / 10
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125 Report
  • Emm...
  • Taken for 1 to 6 months
  • July 23, 2025

"Had 2nd infusion on Monday to prevent bone cancer after breast cancer in '23 and strengthen bones. 1st infusion made me so ill I couldn’t get out of bed to get a bucket to vomit in because I was so weak and dizzy. I started to feel a bit human 5 days later. 2nd infusion has been worse: violent vomiting, chills, aches, headaches, and get this, panic attacks! Yes, I’ve researched it, it’s strongly linked to anxiety, and if you’re someone who’s ever suffered with anxiety or depression, it can cause panic episodes. I can’t stand this drug and am going to ask my oncologist tomorrow for an alternative. Chemo wasn’t this bad."

4 / 10
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1 Report
  • Smi...
  • November 26, 2017

For Hypercalcemia of Malignancy "Went the day before Thanksgiving for my regular shots for my neuroendocrine tumors (NETs)/carcinoid syndrome with mets to liver. Nurse said a 'calcium drip' had been ordered. I figured it was a type of vitamin, although the nurse said some people get mild flu symptoms. I left 40 mins later, went home to a houseful of guests. (I'm the cook for record in our family) About 10:00 that night I felt like a ton of bricks had hit me! The chills, uncontrollable shaking, and violent vomiting began. Every bone and joint in my body ached. I'm now 4 days past treatment and I'm still just 'off.' I'm having trouble searching for words, forgetful, & inexplicably depressed. (sobbing for no reason?) I, too, like the previous post, am furious with my doctor. NEVER AGAIN."

2 / 10
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31 Report

Frequently asked questions

  • Mel...
  • Taken for less than 1 month
  • September 1, 2020

For Osteolytic Bone Metastases of Solid Tumors "I had Zometa for the first time 5 days ago. Had experienced chills on the 2nd night, weakness, and body aches all over. Then on the 5th night, had chills again, weakness, and body aches. Tylenol alternate with Advil helped, but I will never have this medication again. I have no problem with chemo, only this medication. (I have mild osteoporosis and breast cancer.)"

2 / 10
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18 Report
  • TKB...
  • October 18, 2016

For Osteolytic Bone Metastases of Solid Tumors "I have been taking Zometa for breast cancer with metastasis to the bones and have been on it for 8 months now, and I have only had minor aches and pains... no major complications from the drug."

10 / 10
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23 Report
  • rob...
  • Taken for less than 1 month
  • January 22, 2015

For Osteolytic Bone Metastases of Solid Tumors "IV Zometa yesterday. Woke up this morning, body aches, headache, fever, slept all day."

2 / 10
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18 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.