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Zometa and Joint Pain: What Users Say

Joint pain: mentioned by 6 users (13.6%)

Based on user experiences from 44 Zometa reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

chills 22.7%
pain 22.7%
fever 15.9%
flu-like symptoms 13.6%
joint pain 13.6%
body aches 11.4%
bone pain 11.4%
headaches 11.4%
tiredness 11.4%
back pain 9.1%

Reviews for Zometa

Commonly mentioned side effects
  • Anonymous
  • Taken for 6 months to 1 year
  • October 29, 2021

For Osteoporosis "Worst medication I’ve ever had. I got all the severe side effects. Joint and muscle pain, headache, nausea, chest and abdominal pain, chills. This medication is torture. If you want to experience all kinds of body aches and pain, take this medication. I do not recommend it, and I will never take it anymore, even if I was going to die."

1 / 10
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46 Report
  • Jan...
  • December 11, 2016

For Osteoporosis "Had the infusion - 15 minutes - 4 days ago. On the day, felt fine. The next day, thought I was dying, chills, fever, nausea, whole body/bones/joints extremely painful. Woke up every hour and had to drink water. Day 3, felt a lot better and managed to go to work. Day 4, I feel fine. Not sure how effective it will be, will have to have a bone scan in a year's time!"

8 / 10
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50 Report
  • Lor...
  • Taken for less than 1 month
  • April 4, 2016

For Osteoporosis "I have severe arthritis anyway and have a lot of pain, but this was over the top. First day fine, but the next 4 days I was down with bad joint pain, back pain, chills. Not sure I am going to do it again. I have already had 3 breaks and cancer, so I don't know if that's an option for me."

6 / 10
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51 Report

Frequently asked questions

  • dch...
  • Taken for less than 1 month
  • January 29, 2022

For Osteoporosis "I am 65 and consider myself strong and overall healthy. I will never have this infusion again. My side effects included vomiting, diarrhea, fever, severe neck pain, joint pain including thumbs and knees, and my nose hurt. On my oncologist's suggestion, I had a COVID test, and it came back negative for COVID or the flu. Now, after 17 days, I am still experiencing flu-like symptoms, late-day fatigue, and just an overall blah feeling. I had a breast cancer lumpectomy in August and 4 weeks of radiation. I do not see any benefit of this drug and will try something else to get the calcium in my bones as the side effects are absolutely horrible."

1 / 10
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21 Report
  • lis...
  • December 12, 2013

For Osteolytic Bone Metastases of Solid Tumors "I have had three infusions (1 monthly) intravenously administered. No one advised that I should continue taking calcium supplements - good thing I asked! The first infusion led to three days of severe joint pain abating each day. The second infusion had lesser effects, and the third one lessened from the 2nd. Hydrate well before and after the injections. I've had transient chest pain, chills, side pain, episodes lasting for 1-2 minutes."

7 / 10
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49 Report
  • Ele...
  • Taken for less than 1 month
  • September 28, 2017

For Osteoporosis "I received Zometa IV on 9/26/17, after being informed of all the possible side effects. Although I was somewhat concerned, I was pleasantly surprised when, 2 days later, I have experienced nothing worse than a little more joint pain than usual when line dancing last evening. Hopefully, this medication will improve my bone density or at least keep it stable."

8 / 10
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27 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.