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Zometa and Chills: What Users Say

Chills: mentioned by 10 users (22.7%)

Based on user experiences from 44 Zometa reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

chills 22.7%
pain 22.7%
fever 15.9%
flu-like symptoms 13.6%
joint pain 13.6%
body aches 11.4%
bone pain 11.4%
headaches 11.4%
tiredness 11.4%
back pain 9.1%

Reviews for Zometa

Commonly mentioned side effects
  • jak...
  • Taken for less than 1 month
  • June 6, 2019

For Osteoporosis "For four weeks, I had little to no appetite and periods of tiredness. For the first 3 weeks, I was also in a stupor, tired, and weak every day, with nausea daily. Along with these symptoms, for the first 2 weeks, I had on and off fever, chills, headache, no energy, sweats at night. I felt like I was drugged and was weak, unstable, and sick. I would never, never take Zometa again, and I do NOT recommend it."

2 / 10
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115 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • October 29, 2021

For Osteoporosis "Worst medication I’ve ever had. I got all the severe side effects. Joint and muscle pain, headache, nausea, chest and abdominal pain, chills. This medication is torture. If you want to experience all kinds of body aches and pain, take this medication. I do not recommend it, and I will never take it anymore, even if I was going to die."

1 / 10
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46 Report
  • Blo...
  • May 22, 2020

For Osteoporosis "I will never try Zometa again. I had horrific side effects. I passed out 7 hours after home from infusion, my neighbor called paramedics. My blood pressure dropped to 80/58. I’ve had full body ache, headache, sweats, and chills for 3 days so far."

1 / 10
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54 Report

Frequently asked questions

  • Jan...
  • December 11, 2016

For Osteoporosis "Had the infusion - 15 minutes - 4 days ago. On the day, felt fine. The next day, thought I was dying, chills, fever, nausea, whole body/bones/joints extremely painful. Woke up every hour and had to drink water. Day 3, felt a lot better and managed to go to work. Day 4, I feel fine. Not sure how effective it will be, will have to have a bone scan in a year's time!"

8 / 10
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50 Report
  • Lor...
  • Taken for less than 1 month
  • April 4, 2016

For Osteoporosis "I have severe arthritis anyway and have a lot of pain, but this was over the top. First day fine, but the next 4 days I was down with bad joint pain, back pain, chills. Not sure I am going to do it again. I have already had 3 breaks and cancer, so I don't know if that's an option for me."

6 / 10
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51 Report

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  • lis...
  • December 12, 2013

For Osteolytic Bone Metastases of Solid Tumors "I have had three infusions (1 monthly) intravenously administered. No one advised that I should continue taking calcium supplements - good thing I asked! The first infusion led to three days of severe joint pain abating each day. The second infusion had lesser effects, and the third one lessened from the 2nd. Hydrate well before and after the injections. I've had transient chest pain, chills, side pain, episodes lasting for 1-2 minutes."

7 / 10
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  • Smi...
  • November 26, 2017

For Hypercalcemia of Malignancy "Went the day before Thanksgiving for my regular shots for my neuroendocrine tumors (NETs)/carcinoid syndrome with mets to liver. Nurse said a 'calcium drip' had been ordered. I figured it was a type of vitamin, although the nurse said some people get mild flu symptoms. I left 40 mins later, went home to a houseful of guests. (I'm the cook for record in our family) About 10:00 that night I felt like a ton of bricks had hit me! The chills, uncontrollable shaking, and violent vomiting began. Every bone and joint in my body ached. I'm now 4 days past treatment and I'm still just 'off.' I'm having trouble searching for words, forgetful, & inexplicably depressed. (sobbing for no reason?) I, too, like the previous post, am furious with my doctor. NEVER AGAIN."

2 / 10
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31 Report
  • Mel...
  • Taken for less than 1 month
  • September 1, 2020

For Osteolytic Bone Metastases of Solid Tumors "I had Zometa for the first time 5 days ago. Had experienced chills on the 2nd night, weakness, and body aches all over. Then on the 5th night, had chills again, weakness, and body aches. Tylenol alternate with Advil helped, but I will never have this medication again. I have no problem with chemo, only this medication. (I have mild osteoporosis and breast cancer.)"

2 / 10
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17 Report
  • Nan...
  • Taken for less than 1 month
  • March 18, 2021

For Osteolytic Bone Metastases of Solid Tumors "My oncologist, for some reason, changed my medication from Exgiva to this medication. I have been having the worst side effects ever. I have bone pain, stomach pain, fever, and chills. I am on the 5th day, and I’m still experiencing chills and fever. I would never take this medication again. I just wonder how long this is going to last. If I ever get better."

1 / 10
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  • Sed...
  • Taken for 1 to 6 months
  • July 17, 2021

For Osteolytic Bone Lesions of Multiple Myeloma "I was placed on Zometa by my oncologist as a preventive medication to avoid bone lesions and fractures. I was diagnosed with multiple myeloma earlier in the year. I fortunately do not have bone issues at this point, however, my doctor thought it might help with prevention. After my first infusion, I developed severe chills, fever, and terrible calf pain 24 hours later. The fever, chills, and pain fortunately disappeared about a day or two later, but the fatigue lasted for days. Before my second monthly infusion, I drank more water. This did seem to help with avoiding chills and fever, but 24 hours later, I again developed bad calf pain and realized I had edema in my legs. A day later, it is better, but again, I have horrible fatigue and bloating. The side effects of this medicine are worse than those of my cancer meds. I will have to talk to my doctor, as I am not willing to do this every month unless I really have to."

2 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.