Skip to main content

Tizanidine User Reviews & Ratings (Page 4)

Brand names: Zanaflex, Ontralfy

Tizanidine has an average rating of 6.2 out of 10 from a total of 381 reviews on Drugs.com. 48% of reviewers reported a positive experience, while 29% reported a negative experience.

Reviews for Tizanidine

Commonly mentioned side effects
  • ani...
  • February 8, 2016

For Muscle Spasm "Life saver!!!! This muscle relaxer is beyond amazing!!!! I take 4 mg at bedtime, and within 45 minutes, I'm feeling complete relief and fall asleep!!! I don't take a full pill during the day because I literally can't walk straight or fully function after taking a full dose. Works awesome for a sleep aid too!"

10 / 10
Was this helpful?YesNo
58 Report
  • Jol...
  • Taken for 1 to 6 months
  • February 10, 2019

For Muscle Spasm "I had compressed discs in lumbar and cervical spine. I was prescribed this to relax muscles and it was ineffective, and caused fatigue and hair loss - eventually 1/3 of my hair. I had to figure out on my own through research on the web that this was a possible side effect - after just being told by the doctor to take biotin. Hair loss stopped when I stopped taking tizanidine, but no visible regrowth after 3 months."

1 / 10
Was this helpful?YesNo
46 Report
  • 371...
  • July 25, 2008

Tizanidine for Muscle Spasm "I have been on Zanaflex for about 2 months, and it has helped tremendously for migraines, which are caused by bulging discs in my neck. I am taking 4mg three times a day and suffering from only one side effect, which is dry mouth. I really recommend this to others with my condition."

10 / 10
Was this helpful?YesNo
91 Report

Frequently asked questions

  • Sle...
  • Taken for 1 to 6 months
  • September 21, 2019

For Muscle Spasm "Lower back pain after spinal fusion. After ups and downs with back pain resulting in having surgery, my neurosurgeon switched me from Flexeril to Zanaflex because I wasn't sleeping. I am on 4 mg 3x daily, and my experience so far has been good. I totally get good rest at night, and I must say during the day my back doesn't feel like a concrete block, lol. Movement, like walking, is more at ease too, although I'm still a little slow. I'm certainly glad my neurosurgeon switched me. Now gladly, I take the Zanaflex with Aleve. I'm off all narcotics. Overall, I'd definitely recommend Zanaflex."

7 / 10
Was this helpful?YesNo
40 Report
  • Sus...
  • Taken for less than 1 month
  • July 9, 2022

Tizanidine for Muscle Spasm "I had muscle spasms from several neck surgeries. Diagnosed with DDD. I had been using carisoprodol for 21 years. I had to switch to a doctor that wouldn't prescribe carisoprodol. I was prescribed tizanidine, and I am having a really bad experience. I have developed significant anxiety/nervousness. My eyes have gotten so dry that they're red. I can't sleep and experienced chest and right arm pain and a rapid heartbeat. My family is upset with me because I'm so anxious/nervous and have become rude. I never had any of this before this drug. It's destroying my life, and my doctor doesn't care. He doesn't believe any of these side effects. I'm taking 4 mg four times a day. It helps a portion of the muscle spasms. I might like it if I didn't have these disturbing side effects. The carisoprodol was more effective for me."

1 / 10
Was this helpful?YesNo
22 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Mis...
  • November 7, 2020

For Muscle Spasm "Was diagnosed with severe muscle spasms that caused my migraines at age 16. It was an incredible amount of pain. Was put on tizanidine at 2 mg every 8 hours a day. Took Par Pharmaceutical manufacturer all these years, and it has helped a lot - not all the pain is gone, but it almost completely eliminated my migraines. My insurance had to change as of this year, and almost 10 years later I had to switch pharmacies. The new pharmacy gave me Apotex manufactured tizanidine. I started having pain and migraines again, but I thought it was due to the stress of the pandemic - we were several months in at this point. It was only recently when I found some leftovers of my old Par Pharmaceutical tizanidine and took one out of curiosity that I realized the manufacturer change had really set me back - Apotex just doesn't work for me. Never have had bad side effects, aside from minor drowsiness when I started taking it, but that all depends on the person."

9 / 10
Was this helpful?YesNo
31 Report
  • Chr...
  • April 14, 2010

Tizanidine for Muscle Spasm "I have been living with chronic neck, back, and migraine pain for several years now. In the beginning, my doctors had me go to physical therapy, take ibuprofen, or aspirin. None of these things ever really helped. After trying Flexeril and numerous anti-inflammatories, my pain management doctor did an MRI and found that among the many tension knots and twisting of my spine, I had bulging discs in my neck. He gave me Zanaflex to take at night. It knocks me out within 20 minutes but helps relax my back and neck so that I can get restful sleep - been on it for 3 months now! I highly recommend it for continuous back pain and it has even helped with my migraines. Be ready for bed though - very powerful!"

9 / 10
Was this helpful?YesNo
78 Report
  • Anonymous
  • March 22, 2012

Tizanidine for Cluster Headaches "I suffer from migraines and also have difficulty falling and staying asleep. Following, a sleep study, my doctor put me on Zanaflex to help me fall asleep faster and reduced random leg movements during the night. I took it for about a month and it really helped me sleep, although I did have a groggy feeling in the morning that was hard to shake off. However, it aggravated my migraines so that instead of getting them 2 or 3 times a year, I got a migraine every week during the month I was taking Zanaflex, so unfortunately I had to stop taking it."

2 / 10
Was this helpful?YesNo
88 Report
  • Anonymous
  • April 20, 2010

Tizanidine for Cluster Headaches "I have been taking Zanaflex and Desipramine for my daily headaches for about 1 1/2 years. They have greatly decreased the number of headaches and I am very thankful for the relief. I do experience dry mouth and frequent urination but I can live with that. Much easier than the horrible headaches I was experiencing daily."

8 / 10
Was this helpful?YesNo
84 Report
  • Col...
  • Taken for less than 1 month
  • September 9, 2015

For Muscle Spasm "My doctor has just started me on Tizanidine. I can tell the difference already. I have already tried several different medicines for my lower back problems, but Tizanidine has eased the pain well enough for me to get to sleep at night and wake more rested in the morning."

7 / 10
Was this helpful?YesNo
57 Report
  • mjd...
  • August 30, 2014

For Muscle Spasm "Worked great when I first started the meds, but slowly had to increase the dosage for relief. I have fibromyalgia. I take 12 to 16 mg at night. I have started having hallucinations and terrible nightmares. It causes really bad dry mouth. It doesn't help me sleep anymore. I will see if there is something else out there."

6 / 10
Was this helpful?YesNo
64 Report
  • GgG...
  • June 18, 2017

Tizanidine for Muscle Spasm "Strained my rotator cuff, MD acute care practice prescribed 4 mg. I asked both the doctor and pharmacist if it was okay to take with Allegra D. Both said yes. Luckily, I was safe at home. It was scary how sedated I was. I had set an alarm for an appointment 2 hours after taking mess. I got out of bed and could hardly make it to the restroom. Needless to say, I canceled the appointment. Next time I took the medicines separately and broke the 4 mg tablet into 1 mg. I'm no lightweight, but this was too strong for me."

10 / 10
Was this helpful?YesNo
47 Report
  • Ano...
  • April 22, 2017

Tizanidine for Cluster Headaches "I have suffered from daily migraines for over 20 years. Have tried many medicines through the years, and this has really decreased the number I have. Went from daily to once every couple of weeks or so. I take 4 mg at bedtime every night and Imitrex when I feel one coming on."

9 / 10
Was this helpful?YesNo
59 Report
  • Anonymous
  • August 28, 2008

Tizanidine for Muscle Spasm "I am very happy taking Zanaflex. I was originally put on it for migraines, but after a major car accident, they tried to put me on Soma, which caused some side effects. I went back to Zanaflex and have never looked back."

10 / 10
Was this helpful?YesNo
81 Report
  • MiK...
  • September 18, 2009

Tizanidine for Muscle Spasm "I had been having muscle spasms, the Zanaflex helped. I suffer from real bad insomnia, I have been unable to find a medicine that would work for me, and once prescribed Zanaflex, I have been able to sleep every night as long as I have them. So if anyone else suffers from insomnia, maybe they could try Zanaflex, it really helps."

10 / 10
Was this helpful?YesNo
78 Report
  • Mas...
  • Taken for less than 1 month
  • October 11, 2016

For Muscle Spasm "I started to take this medication after telling my doctor about all the failing attempts to reduce my upper back pain. I have scoliosis, and the curvature of my spine is to the right of my shoulder blade. I'm also a very busty lady, and the extra weight doesn't help. After trying out Flexeril at a very high dosage, I was pretty concerned about the side effects of this medication. To my surprise, I feel GREAT! My prescription is 2.0 mg and says 1-2 capsules per night time only as needed. I have been taking only one pill, and after a half hour, I fall into really deep sleep for about 6-8 hours. The only side effect I noticed is a minor stomach ache the next day after I take it. I would recommend this medication to a friend."

10 / 10
Was this helpful?YesNo
48 Report
  • pap...
  • March 22, 2013

For Cluster Headaches "I am on my fifth cluster headache episode. The last time I had one was four years ago, and they generally last about a month. My doctor prescribed the medication to take only at night, and what a difference. Even though I am awakened about an hour after I have been sleeping with the cluster headache, the pain is only about a 3-4 on a scale of 1-10. I am up for about 5 minutes and generally fall back asleep as the pain is dull. One night I didn't take it, and I was awakened with the cluster headache with pain at about a 9, and it lasted for 1 1/2 hours. I will never do that again. I am very happy with this medication!"

10 / 10
Was this helpful?YesNo
62 Report
  • Chr...
  • February 9, 2020

For Muscle Spasm "I saw a neurologist for neck pain and daily headaches (for over 9 years now). I was told I have arthritis and muscle spasms, so I was prescribed tizanidine 2 times a day. I told the doctor they don't work at all on me, so she increased it to 3 times a day! Now I'm having so much weakness and intense headaches. This is not the medication for me! Soma is the ONLY muscle relaxer that's ever worked for me, but my regular doctor will only allow me to be on it for a month (at the most)... and then I have to take a month off of it before she'll prescribe it again! Now I'm off to get Botox injections in my neck and shoulders."

1 / 10
Was this helpful?YesNo
35 Report
  • Dew...
  • February 1, 2020

For Muscle Spasm "I took 1 dose of tizanidine 4 mg and wham! Not with any warning, it hit me. This drug should be taken off the market!!! I almost fell, literally fell asleep standing and just made it to a chair! I had a hallucination, I guess they call it, I saw green lines, my heart rate dropped, my mouth became extremely dry, I could hardly talk, I blacked out for a few minutes, was extremely tired, and the pain! I felt 100 times worse than before. There was a nasty taste in my mouth, then my heart was having palpitations. I became extremely tired very fast, hallucinated, and had no relief, just tired! I have an autoimmune disease (adrenal hypofunction) and was afraid to take ANY med until this got out of my system, it gave me a whopper migraine or pain in my head, anxiety, and my heart rate dropped. Never ever will I take this."

1 / 10
Was this helpful?YesNo
46 Report
  • Cat...
  • February 5, 2016

For Muscle Spasm "I have chronic pelvic pain of unknown origin. This medication reliably relaxes me and knocks me out enough to sleep. It also sedates me enough to have conversations I don't recall and to pass out mid-sentence. Needless to add, perhaps, I do not take it during the daytime. Like many users, it tends to wear off after about 4 hours, and I find an additional dose doesn't promote longer sleep. The sleep I do get is so good that I can put up with the short duration. I am taking the 4 mg tablet. A time-release formulation would be ideal, I think."

9 / 10
Was this helpful?YesNo
47 Report
  • JCa...
  • Taken for 1 to 6 months
  • August 21, 2018

For Muscle Spasm "I was prescribed this medication for muscle spasms after orthopedic surgery to repair a severely crushed lower leg. It was the only one of 3 or 4 meds that worked, but the side effects were bizarre. As I would start to drift off, I would wake and open my eyes, and if I looked straight at the wall beyond the foot of my bed, I would have the sensation that I was looking straight down and was vertical in my orientation. It was very shocking at first because I, of course, would think I was going to fall. I also had extremely lucid dreams that I thought were real even in a waking state. I learned to control the orientation problem, but the dreams were off the charts."

5 / 10
Was this helpful?YesNo
36 Report
  • Ky5...
  • Taken for 6 months to 1 year
  • February 11, 2017

For Muscle Spasm "Tizanidine is an excellent muscle relaxer compared to ones like Flexeril, Robaxin, Baclofen, etc. Soma does work better, but now it's hard to be Rx'd because of FDA overregulating. Anyway, it helps me, gives me great sleep, and helps with headaches. The only side effect I get is dry mouth. Overall, though, I highly recommend this over all the other ones out there! It's done an awesome job for muscle spasms."

10 / 10
Was this helpful?YesNo
44 Report
  • Bam...
  • Taken for 6 months to 1 year
  • October 10, 2019

"My rheumatologist put me on tizanidine 4 mg 3 times a day for fibromyalgia. The tizanidine works well with other meds to help my fibromyalgia. Due to the medicine making me drowsy, I only take it at bedtime. This has helped me tremendously considering I was having major flares with the fibro."

9 / 10
Was this helpful?YesNo
31 Report
  • Sia...
  • Taken for less than 1 month
  • August 4, 2018

For Muscle Spasm "Just came across this site. About five years ago, I was prescribed Zanaflex to help with severe neck pain from facet arthropathy. The first night of taking it and going directly to bed, within ten minutes, I literally could not move. I could not speak or moan to call out to my husband in another room for help, could not move my extremities, felt like I couldn't breathe, etc. I was horrified and helpless throughout the night and was awake the entire night. I notified my doctor and tossed the Zanaflex. I have extreme drug sensitivities, and this was the worst I've ever experienced. There should be a warning about this kind of reaction."

2 / 10
Was this helpful?YesNo
36 Report
  • sli...
  • Taken for less than 1 month
  • March 3, 2018

For Muscle Spasm "I'm 60 years old. This is the worst medication I have ever been given. I took the medication for 2 nights, and that was enough for me. I felt like I was on LSD in the 70s. I was asking my dogs to turn off the lights, like they were human. I saw bugs crawling all over the electrical outlets and anything electric. When I say bugs, I mean thousands of them. NEVER AGAIN."

1 / 10
Was this helpful?YesNo
39 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.