Solifenacin and Fatigue: What Users Say

• Ste...
• Taken for 1 to 6 months
• January 20, 2019

Solifenacin for Urinary Frequency "I took VESIcare for 4 months. VESIcare did improve my overactive bladder, and the urinary urge did decrease. I did not immediately experience side effects except some constipation and reduced stool frequency. I also started getting full nights of sleep without waking to use the loo. That’s the positive part. After 2 months, I started getting occasional liquid diarrhea and then bouts of constipation lasting 3-4 days, then again liquid diarrhea. Throughout this time, lots of gas and cramping. The symptoms were on-off. Then after 3 months, I experienced continuous liquid diarrhea and gas/cramping after every meal. During the space of 30 days, I lost over 5kg in weight and had fatigue, very cold feet, and hands. I stopped VESIcare immediately, and normal bowel movements restored within 5 days. The fatigue and cold extremities have also gone. My conclusions: the VESIcare drug works, but the side effects are intolerable for a significant portion of patients, including myself."

• wet...
• Taken for less than 1 month
• January 13, 2015

Solifenacin for Urinary Incontinence "I am stopping this medication because of the side effects. I am too weak to walk farther than about 20 feet without stopping-bent over and holding on to something. I cannot function this way. The pain in my upper abdomen is awful. Also, I experienced nausea, dizziness, blurred vision, tightness around the chest, and severe fatigue. I loved not having to get up at night, but the near diarrhea caused other problems. I sleep almost 10 hours per night and take frequent naps. I have been told I am pale and walk like a drunken sailor. I am stopping this medication because of the side effects."

• Anonymous
• Taken for 1 to 6 months
• May 7, 2012

Solifenacin for Urinary Incontinence "I take VESIcare for bladder spasms/irritable bladder. VESIcare has helped with the spasms, but I have blurred vision and fatigue. I am going to continue to take VESIcare at this time, but I am thinking I am going to have to do something different soon."

• Ter...
• February 10, 2016

Solifenacin for Urinary Frequency "I had a urinary tract infection and the doctor ordered it to help me urinate less until the antibiotics kicked in. It probably did help for that, but generally I haven't seen a big difference. I would say that I am about the same as I usually am. The first time I took it was in the evening, and I was extremely tired and wanted to sleep around 8 pm (I usually only go to bed/sleep around midnight). Yesterday, I was completely zonked. I slept for most of the day. Last night, I was looking online on my phone and was searching, 'Can a UTI make you tired?' and came across this site. I realized that my vision is blurry (I thought it was just being overtired) and that it can cause 'fatigue.' I hadn't put these down to side effects. I am stopping immediately."

• Ver...
• March 8, 2012

Solifenacin for Urinary Frequency "It worked with taking another overactive bladder medicine. But eventually, I experienced severe fatigue, blurred vision, weight gain, and mostly, it caused me intimacy problems. I discontinued it, got it all back."

• daw...
• Taken for less than 1 month
• May 20, 2023

For Urinary Frequency "I have been prescribed solifenacin as I need to urinate excessively during the night. I have become incontinent and have to wear pads. I have been prescribed solifenacin and have been taking it for two weeks. It has helped immensely. However, the side effects are horrible. Constant heartburn, lower back pain, and a huge stomach. I have been experiencing a lack of energy despite sleeping and feeling depressed. I am usually full of energy and upbeat. I feel the negative reaction is not worth the one positive. In fact, this has made me anxious, and I am hoping to get back to normal ASAP."

• Zoe...
• Taken for less than 1 month
• June 14, 2020

For Overactive Bladder "Have OAB with major urgency issues and have tried almost all the meds. Found one that works (Myrbetriq), but it's not covered by my insurance, so I had to try solifenacin 10 mg since it is. While the drug is very effective, the side effects are so massive that I had to stop after 3 days. The half-life is so long that I'm still feeling most of the side effects days after I've stopped. Raspy voice, feeling like there is a 'fog' in my throat, shortness of breath, tingling in the hands and feet, and excessively tired. Between the extreme fatigue and the sore throat, I was thinking maybe I should get a COVID test, until I realized it was this medication. What a disappointment, as this is one of the two most effective meds I've tried."

• Aaa...
• Taken for 1 to 6 months
• March 14, 2025

Solifenacin for Urinary Incontinence "I've had stress urinary incontinence for over 2 years and never considered taking meds, pissed myself like every week and never slept good because it made me wake up like 2 or 3 times a night, plus having pain in my bladder. Started taking VESIcare 5 ml 5 months ago. Honestly, it's really good. I started seeing changes since the first month. I piss myself rarely now and don't wake up at night, maybe just once a night. I'll continue using it for 5 more months, maybe more. The only bad thing is the side effects, which are so annoying to me: really bad constipation, blurred vision, stomach pain, bad headaches, bad drowsiness, and fatigue, which affects my life because it makes me unable to do anything in my day, plus dryness. Me and my doctor still can't figure out the reason because it started when I was only 15. But anyways, it's a good med, just bad side effects."