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Solifenacin Dosage

Applies to the following strength(s): 5 mg ; 10 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Urinary Incontinence

Initial dose: 5 mg orally once daily
Maintenance dose: 5 to 10 mg orally once daily

Comment:
-This drug may be taken with or without food.

Use: For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency

Usual Adult Dose for Urinary Frequency

Initial dose: 5 mg orally once daily
Maintenance dose: 5 to 10 mg orally once daily

Comment:
-This drug may be taken with or without food.

Use: For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency

Renal Dose Adjustments

-Mild to moderate renal impairment (CrCl greater than 30 mL/min): No adjustment recommended
-Severe renal impairment (CrCl less than 30 mL/min): Dosage should not exceed 5 mg once daily

Liver Dose Adjustments

-Milk hepatic impairment (Child-Pugh A): No adjustment recommended
-Moderate hepatic impairment (Child-Pugh B): Dosage should not exceed 5 mg once daily
-Severe hepatic impairment (Child-Pugh C): Not recommended

Dose Adjustments

Patients taking CYP450 3A4 inhibitors (e.g., ketoconazole, ritonavir, nelfinavir, itraconazole): Dosage should not exceed 5 mg once daily

Precautions

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-This drug should be swallowed whole.
-This drug may be taken with or without food.

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