Invega Trinza and Sexual Dysfunction: What Users Say

• ask...
• Taken for 1 to 2 years
• April 28, 2017

For Schizophrenia "I'm getting Invega, serious side effects in libido (I'm a male), sexual dysfunction, gained 30 kg plus, I can't do sports due to muscle stiffness, and killed all thoughts out of my head, barely can hold a job. No emotions also, I'm a hollow empty shell, a zombie. Can't get drunk. Took my life away. But to say something good, it helped with delusions. I think it is too much price for it."

• ask...
• Taken for 1 to 2 years
• April 28, 2017

For Schizophrenia "I'm getting Invega, serious side effects in libido (I'm a male), sexual dysfunction, gained 30 kg plus, I can't do sports due to muscle stiffness, and killed all thoughts out of my head, barely can hold a job. No emotions also, I'm a hollow empty shell, a zombie. Can't get drunk. Took my life away. But to say something good, it helped with delusions. I think it is too much price for it."

• ano...
• Taken for 1 to 2 years
• April 11, 2019

For Schizophrenia "I have been on this injection since 2017. Received the monthly injections for about three months before my doctor noticed my remarkable stability in mood and made the switch to the tri-monthly injection. When switched to the tri-monthly injection, I noticed that in the third month of being on it, my symptoms of paranoia and delusions would flare up. I've learned to live with it. However, my sex drive is completely gone and my menstrual cycle is too light. As well, there are nights that my insomnia flares up. I have not gained any weight, but I haven't lost any either. To counter all the bad side effects, I have to say that this is the longest that I have been out of the hospital. Besides the odd paranoia/delusions in the third month, I don't hear any voices like I used to or experience a full-blown manic episode (diagnosis is schizoaffective with bipolar tendencies)."

• Bro...
• Taken for 1 to 2 years
• February 22, 2018

For Schizophrenia "This drug is the worst thing that has happened to me. At first, I was overmedicated, this drug caused my tongue to tic the upper part of my mouth. I would have all sorts of hallucinations and delusions, which have gradually gone away as the medicine has been reduced to the recommended dose. Not only to mention, I was only experiencing delusions prior to medication. They have gone away now, but it seems as though my thoughts echo, mimic, and align with sounds I hear. Also, it feels as though there are bugs under my skin due to micro muscle spasm. The worst part about this drug is that it causes you to zone into things, like stare at things or become immobile in your line of vision. Which this only happens occasionally, it really is difficult to drive or hold down a job. I have heightened energy levels with adding Abilify. As this Invega Trinza causes couch lock, not no energy, no motivation, and no drive. At least on this medication, I don’t experience sexual dysfunction."

• dun...
• Taken for 6 months to 1 year
• April 12, 2018

For Schizophrenia "I'm on Invega Trinza for schizophrenia, and it's not bad. I can function somewhat well, but the problem is the side effects such as no sex drive, anhedonia, and no emotions. This is really hard to deal with, but I can't go off it anymore because I already tried and got another psychotic episode."

• Ano...
• Taken for 6 months to 1 year
• November 23, 2021

For Schizophrenia "Well, what can I say? Been on this drug almost a year for schizoaffective. I believe it’s 254 mg every 3 months. I’ve been the most depressed I’ve ever been. Sleeping all day, don’t want to get out of bed, no thoughts, strange dreams, no motivation, reduced sex drive, difficulty finding pleasure in things I used to enjoy. Just an overall bad experience. I can function perfectly fine with medication or drugs, but they told me if I stop taking it, I will get “unwell,” which is rubbish! Enough is enough. I will be refusing treatment from here on out."

• Bra...
• Taken for 6 months to 1 year
• April 27, 2018

"I have bipolar schizoaffective disorder. Tried a lot of pill forms of various medications that had terrible side effects or made my delusions worse. I was on Invega Sustenna for about a year and a half and noticed the effects during the last week of the shot were kind of wearing off. Now that I’m on Trinza, I’ve had a few sexual side effects, but made all my delusions and paranoia/anxiety disappear aside from the occasional Xanax requirement. I also take risperidone 2 mg as needed for the occasional paranoia. It’s given me my life back, though. Costs way too much unless you’re on good insurance. The shot also kind of hurts, but I am terrified of needles and I can handle it. It’s worth it for sure."

• Ann...
• Taken for 6 months to 1 year
• July 18, 2021

For Schizophrenia "This drug works really well to control my positive symptoms like hallucinations, delusions, and paranoia. I still have breakthrough symptoms, but only when very fatigued or stressed, but nowhere near as intense as off medication. I have managed to lose 2 stone (in 6 months) of the 6 stone I put on from taking the Abilify injection. I feel less fatigued, and insomnia isn’t as bad as when taking the other medication. I still have less interest in social situations and relationships, and my sex drive is nonexistent compared to before my illness. All 3 are symptoms of schizophrenia I know can be made worse by medications like these. The main negative is it has increased my prolactin levels to 4 times that of a healthy non-pregnant woman."

• Jas...
• Taken for 2 to 5 years
• August 5, 2022

For Schizophrenia "I am male, 40, and was put on this Invega Trinza for schizoaffective disorder, after being unsuccessful with, at the time, 900 mg Seroquel. I was given Invega Sustenna, 234. Within a day, I was out of psychosis. No side effects. I continued getting it after being released (Sustenna 234). Worked great. I eventually went on Invega Trinza. I've tried Risperdal, Seroquel, Abilify, and some other ones. Started Seroquel (2008-2017). Since 2017 till August 2022, I've had success on Invega Trinza (3-month shot). I feel nice and calm, not drugged out at all. The increase in prolactin causes sexual dysfunction. The doctor added Abilify (10 mg). Less sex drive but still active. I've tried a lot, so I was broken in as far as trying antipsychotics. If this is your first try on antipsychotics, you will probably have different results. I'm also on Effexor 150, Lamictal 300, Abilify 10, Naltrexone 50, and Lipitor. No more depression/mania. Be warned, once you take this med for more than a year, it's going to be really hard getting off it, if you can. Good luck!"

• Anonymous
• Taken for 1 to 2 years
• November 23, 2024

"I’ve been on Invega for about two years. I started with Invega Sustenna (shot once a month) for about 6 months, then switched to Trinza. Overall, the drug has worked really well for me until I began to develop tardive dyskinesia. About 6 months ago, I also had a mild manic episode on the second-to-lowest dose. Because of this, they upped my dose, and I’ve gained 30 lbs in 6 months and have no sex drive. Such a better option compared to Haldol and lithium, which made me gain 60 lbs and had so many other side effects. I lost 30 lbs when they lowered my dose to the second-lowest of Invega, but unfortunately gained it all back when they upped the dose. I hate taking medication, this is all still kinda new to me, and I want to eventually get off meds, but my psychiatrist won’t let me."

• Anonymous
• Taken for 6 months to 1 year
• December 27, 2022

For Schizophrenia "I have had to deal with sexual dysfunction and weight gain on this horrible drug."