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Xtampza ER User Reviews & Ratings (Page 5)

Xtampza ER has an average rating of 3.9 out of 10 from a total of 169 reviews on Drugs.com. 24% of reviewers reported a positive experience, while 62% reported a negative experience.

Reviews for Xtampza ER

Commonly mentioned side effects
  • Pea...
  • Taken for 1 to 6 months
  • September 9, 2018

For Chronic Pain "Works great but causing a severe sore throat. Taken steroids and antibiotics with no relief. Everyone, including the pharmacist, says it would not cause a sore throat, but ever since I started these, I have had a severe chronic sore throat. If it wasn't for the sore throat, I would love it. It helps with back pain much more than MS-Contin."

7 / 10
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32 Report
  • Rog...
  • September 15, 2017

For Chronic Pain "Dose is two 36 mg every 12 hours. Plus breakthrough meds. The Xtampza doesn't last the full time, so I've found that switching to 1 pill every 6 hours DOES WORK because there is a steady stream of meds, plus the breakthrough as needed. Hope this will help."

8 / 10
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32 Report
  • Con...
  • Taken for 1 to 2 years
  • April 14, 2022

For Chronic Pain "Insurance company switched coverage to Xtampza about 18 months ago. Never worked well for pain relief. I complained to my PM doctor, who was totally unsympathetic. About 2 months ago, my PM doctor was popped by the DEA and lost his practice. Had to find another PM (so few left). Ran out of Xtampza. What an unexpected bonus. The massive migraines that I blamed on sinus infections disappeared. I realized that by taking Xtampza, I was at the same level of pain as using it. However, without it, I feel better and no longer have massive migraines and constant confusion. This stuff is garbage, and I will never take it again."

1 / 10
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16 Report

Frequently asked questions

  • Tee...
  • Taken for less than 1 month
  • July 22, 2019

For Chronic Pain "I started taking this about two weeks ago, and I'm very happy. It doesn't completely eliminate all pain, but nothing will. I can walk most of the day with limited amounts of pain. For me, the morning is the roughest, because it takes about 4 hours to peak for me, that's with a handful of almonds with each dose of twice daily, 13.5 mg. I'm glad my doctor made this switch."

9 / 10
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35 Report
  • Dia...
  • April 21, 2018

For Chronic Pain "I have constant, chronic severe facial pain from a head and neck injury that was recently helped in a major way with stimulator implant surgery in Denver. Still need pain meds but much lower dose. Forced to use this drug through the insurance company's refusal to continue providing Oxy ER. Was put on Xtampza for about 2.5 months, gained 25 pounds fast without changing diet, extreme headaches with pressure like never before, every joint hurt. Doctor said to maintain 18 mg/2x day dose anyway. Took one more week, gained 5 pounds more, and said enough. Got off it using leftover fast-acting, now down to just occasional doses for severe breakthrough pain. Found out all my allergies and general body aches the past 13 years have been due to pain meds and my body's reaction to them, so once I'm off, symptoms disappear. Wouldn't have known that without Xtampza, but my headaches aren't easing after being off it for a month, plus going off Topiramate. Will these headaches ever get better, or is this my new normal?"

1 / 10
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26 Report

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  • Jen...
  • Taken for less than 1 month
  • February 16, 2022

For Chronic Pain "After being on Perc 15 mg for several years, which worked very well for the pain, but the doctor said I had to switch because it's a short-term medication. So we tried a few other long-term meds, which help but weren't lasting the full length that they were supposed to last for, so I asked my doctor to put me on another long-term medication, and he put me on Xtampza ER 36 mg, and this new medication, Xtampza 36 mg, does not even work. It doesn't touch the pain I'm in. Why would you prescribe this medication to anyone? It's junk, it doesn't work."

1 / 10
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  • Bam...
  • July 24, 2017

For Chronic Pain "Works well for me after finding a dose that was equivalent to the Oxy regimen I was on before being switched to this. Definitely recommend the diet recommended in the directions, works better that way."

9 / 10
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32 Report

More FAQ

  • Chr...
  • Taken for less than 1 month
  • June 15, 2018

For Chronic Pain "Have just started, seems to be working as advertised. I have had chronic pancreatitis for 12 years and have struggled for years to get pain under control. Like I said before, just started taking it. It has been a week, I don’t have to take as much breakthrough medicine. I can finally sleep more than 4 hours, yeah!!!"

7 / 10
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  • Cor...
  • Taken for less than 1 month
  • March 14, 2021

For Chronic Pain "I have been getting physical therapy, doing physical therapy anyway as epidermal delta cortisone shots into shoulder, back, and well-diagnosed pain, varicose veins, rheumatoid arthritis, torn tendon, and neuro-pain. I've been taking OxyContin 80 mg CR every 12 hours, with lidocaine patch, until the OxyContin was not covered, so I was now prescribed Xtampza ER 36 mg twice daily every 12 hours. It made me have withdrawals, sweats, changes in behavior, and not much analgesic pain help. This medicine makes people bloated and drag their butt around in pain all day. And nobody wants to take something that just gives poor sleep from pain that keeps you awake and bad dreams of how you still have pain. It should be remade or off the market of pharma for false advertising."

1 / 10
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  • Bad...
  • Taken for 1 to 6 months
  • April 26, 2018

For Chronic Pain "Xtampza works very well for being extended release. I have half the breakthrough pain and flare-ups taking this med. Take it around the clock on time. Be patient with this med and find out what dose works best. It changed my life drastically for the better."

8 / 10
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32 Report
  • LDM...
  • Taken for 1 to 2 years
  • March 26, 2022

For Chronic Pain "Have been on 40 mg ER of OxyContin 2 x a day, along with ten Percocet 10/325 and many other drugs for severe chronic pain for 20+ years. Was made to switch to Xtampza 36 ER 2x a day and 5 Percocet. The Xtampza ER is worthless! Shame on whoever decides that a drug works or does not, as every individual person's body is different, as are their diseases. For people who are responsible and do not have a life without adequate pain relief, you are making us prisoners in our own bodies. Even with OxyContin 40 ER 2x a day and all the other meds, most of us still suffer plenty. I am not even 60 and can hardly move with new drug changes. Have had over 40 surgeries and am full of hardware. I do not like having to eat the high fat with Xtampza twice a day. When you are in severe to debilitating pain, you have no appetite. I am probably 10 pounds overweight but do not need to carry any more weight with eating high fat twice a day, as I eat healthy. Suicide rates will increase with this new drug."

1 / 10
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15 Report
  • Lon...
  • July 10, 2017

For Chronic Pain "Have had chronic lower back pain for over a decade. Insurance co. made me switch to Xtampza from OC. The first few weeks were a bit of a challenge because we had to find what dosage strength and dosing frequency was best for me. But once we got through this, I find the drug works well when I use it as directed, particularly as it relates to diet. Also, I have my backup of fast-acting pills when I have breakthrough pain. I think people that say this drug doesn't work aren't being dosed appropriately, or they have just been on high doses of OC alongside short-acting narcotics for so long that they are just too far along to be helped by anything new because their bodies have just gotten so used to their incredibly high dose OC regimen. Sorry, but push through."

8 / 10
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38 Report
  • BBQ...
  • Taken for 2 to 5 years
  • January 12, 2021

For Chronic Pain "Was on OxyContin 20 mg twice a day. Percocet twice a day as needed, 5/325 mg. Never had to increase. Was switched to Xtampza a few years ago, started on 18 mg twice a day, took time as no conversion chart between both meds, so ended up taking 27 mg twice a day. With food, worked but very strong, couldn't function, so just decreased to 18 mg twice a day, clear mind, pain-free and taking fatty food with it as that's how it works. Switching between meds takes time, but will work, take it with food to help plasma levels, it's strong, so be careful."

10 / 10
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22 Report
  • Ros...
  • Taken for less than 1 month
  • October 5, 2022

For Chronic Pain "Xtampza ER 9 mg didn’t help with my chronic pain at all. It did, however, make my anxiety level increase greatly and my blood pressure go up. These side effects are such that I’ll be talking to my doctor about an alternative pain medicine."

1 / 10
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12 Report
  • nan...
  • Taken for less than 1 month
  • March 26, 2021

For Chronic Pain "Have been taking this type of pain med for 1 week. Switched off Percocet. I have chronic neck, spine, and leg pain, in addition to a brain injury. This medication is not only expensive, I am back to pain that I had previously. Movement hurts: lifting, spine, right leg, and brain is like I felt after surgery. This is a shame and expensive."

1 / 10
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17 Report
  • Mik...
  • Taken for 5 to 10 years
  • May 23, 2024

For Pain "I have lived with chronic pain for over 20 years, failed fusions and other spinal surgeries. Xtampza isn’t as effective as the OxyContin equivalent, but it takes my pain down to a level that keeps me reasonably functional. I take the morning dose with toast and peanut butter, it’s enough fat to make it work. It takes 60-90 minutes, and the 13.5 mg can provide 6-7 hours of relief. It’s possible to get authorization to take it every 8 hours if you metabolize quickly. 800 mg of Ibuprofen with the PM dose is excellent, but many can’t tolerate this med. I try to limit it to every other day and always before a full meal, usually at 6 pm supper. My doctor doesn’t believe in IRs or “breakthrough pain,” so it’s as good as it’s going to get. I feel lucky to not be totally incapacitated and manage more “good” days than “bad.”"

7 / 10
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6 Report
  • Bhu...
  • Taken for 1 to 6 months
  • November 18, 2020

For Chronic Pain "New pain doctor did not want to increase oxycodone to 4 times per day. Long story short, he prescribed Xtampza 13.5 @ 1 twice a day with 1 oxycodone 10 mg per day for breakthrough pain. I have to say it's not awful. It took a few days to kick in, but there have even been a few days that I didn't need the oxycodone! Chronic pain is awful!"

7 / 10
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17 Report
  • Jim...
  • Taken for 6 months to 1 year
  • August 30, 2018

For Chronic Pain "I was taking 30 mg of OxyContin per day when Cigna suddenly stopped covering it. The doctor switched me to Xtampza ER 13.5 mg twice a day, and I was quite apprehensive after being on OxyContin for the past few years for an inoperable chronic back condition. I have been very happy with the new medication. It works as well as what I had been taking, and it seems to last longer. With OxyContin, I knew when the time was up, with this medication, I can go two to three hours over the time for the next dose and not have a problem. I also have the feeling that getting off this medication will be easier than getting off the OxyContin. I know it's basically the same medication, but it just seems to work differently."

8 / 10
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32 Report
  • All...
  • Taken for less than 1 month
  • March 20, 2025

For Chronic Pain "A placebo could be more effective than this medication! Currently, there is a national shortage of MS-ER, causing my pain specialist to prescribe this useless medication. 5 years ago, the same doctor prescribed Xtampza ER, and I couldn’t function due to the excruciating pain 24/7! He actually admitted aloud that it was a huge mistake, so why I have been prescribed this yet again defies all logic and proper medical treatment. 18 mg, twice daily. An OTC Tylenol is more effective; in other words, it does not do anything to relieve ANY pain, but it certainly caused headaches, nausea, vivid nightmares, and extreme fatigue! Why is this medication still on the market? Very expensive, worthless for pain relief! I am currently unable to get out of bed, and my pain level is off the charts…"

1 / 10
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2 Report
  • ano...
  • November 28, 2020

For Chronic Pain "I have been on OxyContin for many years for chronic pain. Insurance forced me off the brand name to a still decent oxycodone ER, which worked well. Now the distributor ran out, not sure if it will ever be restocked... (has been on back order forever now) my only option left was Xtampza ER, which, I agree with everybody else, does not work the same as OxyContin. I had to switch to Xtampza fairly quickly and now experiencing rapid heartbeat, sleeplessness, and it only seems to work from the neck up for pain effectiveness... awful stuff! I'm almost ready to pay out of pocket for the better medication."

3 / 10
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16 Report
  • Kim...
  • July 1, 2022

For Chronic Pain "I was taking Percoset 10, 150 pills a month. Without consulting me, my doctor changed it to 120 pills and 30 Xtampza. He said to take 1 at bedtime and it should help me through the night. Maybe it did for the first couple of weeks, then nothing I could feel. I asked to be put back on the original prescription and was told they wouldn't do it. After 4 months of demanding not to take Xtampza, I am looking for a new pain management doctor."

2 / 10
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10 Report
  • Kno...
  • Taken for 1 to 6 months
  • June 17, 2024

For Pain "Xtampza ER 13.5 mg has worked great for me! Although it doesn't last the whole 12 hours every time, it still does the job. I also have to double the dose sometimes and take it with peanut butter. I was on oxycodone, 15 mg 5 times a day and felt I needed more. Plus, it was hurting my liver, gallbladder, and pancreas. Now Xtampza changed all that. I'm asking my doctor for a higher dose at my upcoming follow-up."

9 / 10
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5 Report
  • Con...
  • Taken for less than 1 month
  • August 21, 2021

For Pain "Worthless for pain relief. Doesn't matter how many you take. Ran out of immediate release oxycodone before the weekend because my pain management doctor quit and the new doctor couldn't get all of the patients taken care of."

1 / 10
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12 Report
  • I...
  • Taken for less than 1 month
  • October 24, 2017

For Chronic Pain "I am at the end of my 1st week into my second week, day two. Like most of you, I cried in the doctor's office for fear of the level of pain I’d have to endure daily. My pain was as bad as all of yours. My first 4 days were awful, then each day a bit better. I finally began taking 1/39 mg capsule every 3/0.5 hours, through 6 capsules a day + 4/10 mg breakthrough pain tablets. As the days passed, I found I needed less breakthrough daily, and my daily pain was controlled like never before. Don’t get me wrong, I endure pain and not every day is perfect. But yes, I am very pleased and wish I tried them sooner when my OxyContin began to die down within 5/6 hours. The breakthrough was more of a joke. Xtampza gave me my life back."

9 / 10
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28 Report
  • Anonymous
  • Taken for 1 to 6 months
  • January 4, 2023

For Chronic Pain "I don’t like this drug. It provided no relief for me. I gave it an honest try but no benefit from it at all. My insurance doesn’t want me to get the OxyContin ER, and this was one of the suggestions. Miserable."

2 / 10
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8 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.