Skip to main content

Xtampza ER and Anxiety: What Users Say

Anxiety: mentioned by 6 users (3.6%)

Based on user experiences from 169 Xtampza ER reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 11.8%
headaches 7.7%
dizziness 4.7%
nightmares 4.7%
pain 4.7%
weight gain 4.1%
withdrawal 4.1%
anxiety 3.6%
diarrhea 3.6%
depression 3.0%

Reviews for Xtampza ER

Commonly mentioned side effects
  • Fee...
  • Taken for less than 1 month
  • December 23, 2020

For Chronic Pain "After taking MS Contin for 5 years, I thought it was losing effectiveness and made the mistake of telling my doctor this. He switched me to this Xtampza ER. Horrible drug. It made me sick to my stomach, headachy, general malaise physically, anxious, and somewhat depressed. It wasn't any more effective than the MS Contin, and the pain relief it gave me wore off in 4 hours. Due to the side effects, I had no life. I didn't feel well enough to do simple things like go to the grocery store, do dishes, etc., which the MS Contin allowed me to do. I was taking it for 2 weeks, and the symptoms were getting worse, not better. I just wanted my old medicine back, and it was a big struggle to get it back. I got the sense from my doctor that this Xtampza ER was the king of pain medication. For me, it was far from that."

1 / 10
Was this helpful?YesNo
227 Report
  • Sle...
  • Taken for 1 to 6 months
  • February 7, 2019

For Chronic Pain "In a word...awful. I've been on 2x18mg Xtampza ER for over a month now, after my sadistic insurance co refused to cover OxyContin, which I've been taking 2x20mg since 07 for severe pelvic floor pain. While Xtampza is designed to avert abuse, it most definitely is not designed for any credible chronic pain relief. First and foremost, it's doing very little for my pain. It takes FOREVER, like 2+ hours(!), to work, and lasts 3-4 hours, at best. I'm being generous saying it 'works', since it barely takes the edge off my pain. I still have to take breakthrough meds, even while this junk is supposed to be in full effect. I regularly experience strong side effects described by other reviews, including headaches, nausea, sleeplessness, and high anxiety. It's amusing to hear the claims of this med being 'exactly the same' as OxyContin - the one thing that actually worked."

1 / 10
Was this helpful?YesNo
79 Report
  • Rlz...
  • Taken for less than 1 month
  • May 7, 2022

For Chronic Pain "This is a horrible medication, it's tearing my stomach up, and I already recently was hospitalized with a bleeding ulcer a few months back. I had been recovering, and now my stomach hurts again, plus I'm having several gallbladder attacks every day due to having to eat high-fat food trying to get it to work, which it doesn't anyway. I'm tired of being treated like an addict by insurance companies, etc. In 16 years, I have NEVER abused my medicine, and these insurance companies just assume pain patients all abuse pain meds. This Xtampza causes constant headache, general malaise, dizziness sometimes, nervousness sometimes, and I have body aches in places I haven't hurt before, like severe cramps in my toes. I feel withdrawn, like it takes all I have to have a conversation. They need to worry about the fentanyl coming across the border and leave us pain patients that have no red flags of abusing their medicine alone!!!"

1 / 10
Was this helpful?YesNo
28 Report

Frequently asked questions

  • Inj...
  • Taken for less than 1 month
  • April 11, 2023

For Chronic Pain "This product should not even be on the pain medication list for doctors. Nothing but nausea, headache, anxiety, and added pain!!! Don’t waste your money because most insurance doesn’t cover it!!! GARBAGE!!!"

1 / 10
Was this helpful?YesNo
20 Report
  • Pat...
  • November 2, 2017

For Chronic Pain "Been on this for months, just don't understand why I'm having side effects, as my doctor says everything is the same, just time release. The first 4 weeks, headaches so severe I couldn't put in a full day. I'm a secretary, so on the computer screen all day. This is what gave me the headaches I believe, along with meds. I also got very nauseous, dizzy, and extremely moody. I put on 20 pounds once I was told to eat a fatty diet with this meal, as I guess the fats help break down the medicine, doctor never told me this, but helped a lot with being sick all the time. Doctor finally listened, as I was tired of being in a cloud all day. Also, anxiety and sleeplessness... This medicine may work for some, just not me."

4 / 10
Was this helpful?YesNo
39 Report
  • Ros...
  • Taken for less than 1 month
  • October 5, 2022

For Chronic Pain "Xtampza ER 9 mg didn’t help with my chronic pain at all. It did, however, make my anxiety level increase greatly and my blood pressure go up. These side effects are such that I’ll be talking to my doctor about an alternative pain medicine."

1 / 10
Was this helpful?YesNo
12 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.