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Xtampza ER and Nightmares: What Users Say

Nightmares: mentioned by 8 users (4.7%)

Based on user experiences from 169 Xtampza ER reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 11.8%
headaches 7.7%
dizziness 4.7%
nightmares 4.7%
pain 4.7%
weight gain 4.1%
withdrawal 4.1%
anxiety 3.6%
diarrhea 3.6%
depression 3.0%

Reviews for Xtampza ER

Commonly mentioned side effects
  • Bel...
  • Taken for less than 1 month
  • May 6, 2020

For Chronic Pain "I found this information about this pain control medication not working to be accurate. I've been on Oxycodone for over 8 years, and my pain has increased with time. I started this with the idea that I would finally get some pain relief, but it's nothing like what the PA told me it was. It does not offer me extended pain relief, but it does cause me not to sleep, or if I do fall asleep, I have terrible nightmares. It's terrible on my stomach, and I've tried taking it with many different foods, and now I have this static-sounding noise that is terrible. I was only given enough for a few weeks to see if it helps, but it doesn't. Because I don't want to start on Fentanyl, I'm going back to what I was taking because this is so much worse and still no pain relief. Why is this even an option for chronic pain relief."

1 / 10
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  • In ...
  • Taken for less than 1 month
  • January 16, 2020

For Chronic Pain "This has to be taken with a fatty, high-calorie meal for it to work correctly, and anyone in pain knows that eating is the last thing you want to do. I’m force-feeding myself, gained 13 pounds in two weeks. Xtampza is making me have uncontrollable diarrhea and gas that I haven’t left home since I started it for fear I would poop myself in public. I get no warning, it just comes out as if I’ve lost control of my bowels. I’ve noticed a few undigested pill capsule shells as well. The nightmares! Last night I was being chased by my mother's ex-husband with a shotgun. I don’t know what happened, but I do know that’s not normal. Overall, this is a horrible medication! It doesn’t work, makes you rapidly gain weight, hurts your tummy, makes you poop your pants, can’t digest the shells, and gives you nightmares... yeah, I’m good... just give me back the meds that work already!"

1 / 10
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102 Report
  • CJa...
  • February 16, 2020

For Chronic Pain "Just started Xtampza because of insurance demands. I’d been on OxyContin 20 years for chronic back pain and fractures. Xtampza is not doing the job. I’m having horrific nightmares and a racing heart. The pain relief is minimal. I’m going back to OxyContin even if I have to pay the total price without insurance."

2 / 10
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44 Report

Frequently asked questions

  • Gem...
  • Taken for less than 1 month
  • April 19, 2020

For Chronic Pain "Had spinal fusion surgery that left me with more pain than I had pre-surgery. I was burning through 10/325 Percocet, so my pain management switched me to Xtampza 18 mg. 1st night had such a bad nightmare I refused to go back to sleep. This med caused insomnia on some days or sleep with horrific dreams. As for pain, it did manage my pain, but I hope I am not required to be on it for a long amount of time. I mixed it with 1 tablespoon of peanut butter and it seems to work well that way. It is also on the pricey side, even with insurance."

8 / 10
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43 Report
  • Gem...
  • Taken for less than 1 month
  • April 19, 2020

For Chronic Pain "Had spinal fusion surgery that left me with more pain than I had pre-surgery. I was burning through 10/325 Percocet, so my pain management switched me to Xtampza 18 mg. 1st night had such a bad nightmare I refused to go back to sleep. This med caused insomnia on some days or sleep with horrific dreams. As for pain, it did manage my pain, but I hope I am not required to be on it for a long amount of time. I mixed it with 1 tablespoon of peanut butter and it seems to work well that way. It is also on the pricey side, even with insurance."

8 / 10
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43 Report

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  • Kri...
  • Taken for less than 1 month
  • January 14, 2018

For Chronic Pain "I suffer from severe, chronic back, neck, and shoulder pain. This is one of the worst medications I've ever taken. The nausea and dizziness are awful. If that were the only negative side effect, I think I could live with it, though. What I found extremely disturbing was the psychological effects. After only two doses, I had terrifying nightmares that were difficult to awaken from. I, uncharacteristically, felt like Alice in Wonderland in an extremely unpleasant manner while I was awake. I can't believe this medication is on the market. Not to mention, it did absolutely nothing to help with pain."

1 / 10
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39 Report
  • Xta...
  • Taken for less than 1 month
  • February 13, 2022

For Pain "I wish I had thought to Google these reviews before I threw away six hundred plus dollars on this pathetic excuse for pain meds. Didn't get I had to jump through a hoop when taking it, and when I found out it made no difference. Vivid, disturbing dreams as well. Zero pain relief. This manufacturer should be sued. False advertising."

2 / 10
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19 Report
  • She...
  • February 16, 2018

For Chronic Pain "Not only is this a very expensive medication, even with insurance, the 18mg capsule twice a day does not help my pain one bit. What it does help me to have are abnormal, very real, and terrifying nightmares that leave me howling for help in the middle of the night or yelling myself awake if I lie down for a nap. As someone else mentioned, these dreams are hard to wake up from on your own. Nightmares like half-man, half-beasts after me, a boat ride spinning out of control down an abyss, inanimate bizarre objects coming to life and after me, odd places I've visited before but haven't. I cannot deal with this, not at all, and I will not take anymore of these. At this point, I would rather deal with chronic pain than chronic nightmares and losing sleep. Acupuncture may be my next step since positively nothing medical has helped one iota. More meds have worse side effects, and cheap generics do nothing. So now what? I give up."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.