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Nitroglycerin Rectal Ointment

Generic Name: Nitroglycerin Rectal Ointment (NYE troe GLIS er in)
Brand Name: Rectiv

Medically reviewed on July 4, 2018

Uses of Nitroglycerin Rectal Ointment:

  • It is used to treat anal pain.
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Nitroglycerin Rectal Ointment?

  • If you have an allergy to nitroglycerin or any other part of nitroglycerin rectal ointment.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have any of these health problems: Anemia, raised pressure in the head (like with bleeding in the brain or head injury), or recent heart attack.
  • If you have heart problems.
  • If you have low blood volume.
  • If you are taking any of these drugs: Avanafil, riociguat, sildenafil, tadalafil, or vardenafil.
  • If you are taking any of these drugs: Dihydroergotamine, ergonovine, ergotamine, or methylergonovine.
  • If you are breast-feeding or plan to breast-feed.

This is not a list of all drugs or health problems that interact with nitroglycerin rectal ointment.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take nitroglycerin rectal ointment with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Nitroglycerin Rectal Ointment?

  • Tell all of your health care providers that you take nitroglycerin rectal ointment. This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how nitroglycerin rectal ointment affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
  • Have your blood pressure checked often. Talk with your doctor.
  • This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take nitroglycerin rectal ointment.
  • Avoid drinking alcohol while taking nitroglycerin rectal ointment.
  • If you are 65 or older, use nitroglycerin rectal ointment with care. You could have more side effects.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using nitroglycerin rectal ointment while you are pregnant.

How is this medicine (Nitroglycerin Rectal Ointment) best taken?

Use nitroglycerin rectal ointment as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Wash your hands before and after use.
  • Cover your finger with plastic-wrap, a surgical glove, or a finger cot.
  • Use the dosing guide on the box to put the ointment on your covered finger.
  • Place the finger with the ointment on it into the anal canal up to the first finger joint.
  • Smear the ointment inside the anus.
  • You may also put the ointment on the outside of your anus.
  • Keep out of your mouth, nose, vagina, and eyes (may burn).

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

See also: Dosage Information (in more detail)

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad dizziness or passing out.
  • Very bad headache.
  • Fast or slow heartbeat.
  • Flushing.
  • Blurred eyesight.
  • Dry mouth.
  • Sweating a lot.
  • Pale skin.
  • Very upset stomach or throwing up.
  • A heartbeat that does not feel normal.
  • Restlessness.
  • Feeling very tired or weak.

What are some other side effects of Nitroglycerin Rectal Ointment?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Dizziness.
  • You may have headaches when you start taking nitroglycerin rectal ointment. Most of the time it gets better with time. Do not change how you use nitroglycerin rectal ointment to avoid these headaches. Talk with your doctor for ways to lessen this side effect.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

See also: Side effects (in more detail)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Nitroglycerin Rectal Ointment?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep the tube tightly closed. Use within 8 weeks of first opening.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about nitroglycerin rectal ointment, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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