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Xyzal Allergy 24HR Side Effects

Generic Name: levocetirizine

Note: This document contains side effect information about levocetirizine. Some of the dosage forms listed on this page may not apply to the brand name Xyzal Allergy 24HR.

In Summary

More frequent side effects include: drowsiness, fatigue, and nasopharyngitis. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to levocetirizine: oral solution, oral tablet

Along with its needed effects, levocetirizine (the active ingredient contained in Xyzal Allergy 24HR) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking levocetirizine:

Less Common

  • Bloody nose
  • fever

Incidence Not Known

  • Anxiety
  • attack, assault, or force
  • blurred or loss of vision
  • cough
  • dark urine
  • decrease in the frequency of urination
  • decrease in urine volume
  • difficult or labored breathing
  • difficulty in passing urine (dribbling)
  • difficulty with swallowing
  • disturbed color perception
  • dizziness
  • double vision
  • dry mouth
  • fast, irregular, pounding, or racing heartbeat or pulse
  • general tiredness and weakness
  • halos around lights
  • hives or welts
  • hyperventilation
  • irritability
  • itching skin
  • joint or muscle pain
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • light-colored stools
  • nausea and vomiting
  • nervousness
  • night blindness
  • overbright appearance of lights
  • painful urination
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • restlessness
  • seizures
  • shaking
  • skin rash
  • tightness in the chest
  • trouble with sleeping
  • tunnel vision
  • upper right abdominal or stomach pain
  • yellow eyes and skin

Some side effects of levocetirizine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common

Less Common

  • Body aches or pain
  • congestion
  • diarrhea
  • dryness or soreness of the throat
  • earache
  • hoarseness
  • redness or swelling in the ear
  • tender, swollen glands in the neck
  • voice changes

For Healthcare Professionals

Applies to levocetirizine: oral solution, oral tablet

General

The most frequently reported side effects were: somnolence, nasopharyngitis, fatigue, dry mouth, and pharyngitis (in 12 years and older); pyrexia, somnolence, cough, and epistaxis (in patients 6 to 12 years); pyrexia, diarrhea, vomiting, and otitis media (in patients 1 to 5 years); diarrhea and constipation (in patients 6 to 11 months).[Ref]

Nervous system

Common (1% to 10%): Somnolence, dizziness, headache

Uncommon (0.1% to 1%): Paresthesia, syncope

Rare (0.01% to 0.1%): Convulsion, movement disorder

Very rare (less than 0.01%): Dysgeusia, tremor, dystonia, dyskinesia

Frequency not reported: Orofacial dyskinesia, myoclonus, extrapyramidal symptoms

Postmarketing reports: Febrile seizure[Ref]

Ocular

Very rare (less than 0.01%): Accommodation disorder, vision blurred, oculogyration

Postmarketing reports: Visual disturbance[Ref]

Respiratory

Common (1% to 10%): Nasopharyngitis, pharyngitis, cough, epistaxis, rhinitis

Postmarketing reports: Dyspnea[Ref]

Gastrointestinal

Common (1% to 10%): Dry mouth, diarrhea, vomiting, constipation, abdominal pain

Postmarketing reports: Nausea[Ref]

Other

Common (1% to 10%): Fatigue, pyrexia, otitis media

Uncommon (0.1% to 1%): Weight increased, asthenia, malaise

Rare (less than 0.1%): Edema

Frequency not reported: Stillbirth

Postmarketing reports: Vertigo[Ref]

Psychiatric

Uncommon (0.1% to 1%): Agitation

Rare (0.01% to 0.1%): Aggression, confusion, depression, hallucination, insomnia

Very rare (less than 0.01%): Tic, enuresis

Postmarketing reports: Suicidal ideation, nightmare[Ref]

Genitourinary

Very rare (less than 0.01%): Dysuria

Postmarketing reports: Urinary retention[Ref]

Cardiovascular

Rare (less than 0.1%): Tachycardia

Frequency not reported: Severe hypotension

Postmarketing reports: Palpitation[Ref]

Dermatologic

Uncommon (0.1% to 1%): Pruritus, rash

Rare (0.01% to 0.1%): Urticaria

Very rare (less than 0.01%): Angioedema, fixed drug eruption

Frequency not reported: Acute generalized exanthematous pustulosis[Ref]

Hepatic

Rare (less than 0.1%): Hepatic function abnormal, transaminases increased, bilirubin increased

Frequency not reported: Cholestasis

Postmarketing reports: Hepatitis[Ref]

Hematologic

Very rare (less than 0.01%): Thrombocytopenia[Ref]

Immunologic

Rare (0.01% to 0.1%): Hypersensitivity

Very rare (less than 0.01%): Anaphylactic shock[Ref]

Renal

Frequency not reported: Glomerulonephritis[Ref]

Metabolic

Postmarketing reports: Appetite increased[Ref]

Musculoskeletal

Postmarketing reports: Myalgia, arthralgia[Ref]

References

1. "Product Information. Xyzal (levocetirizine)." UCB Pharma Inc, Smyrna, GA.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

More about Xyzal Allergy 24HR (levocetirizine)

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