Prinivil Side Effects
Generic name: lisinopril
Medically reviewed by Drugs.com. Last updated on Oct 26, 2022.
Note: This document contains side effect information about lisinopril. Some dosage forms listed on this page may not apply to the brand name Prinivil.
Common side effects of Prinivil include: dizziness, hypotension, hyperkalemia, increased blood urea nitrogen, and increased serum creatinine. Other side effects include: headache. Continue reading for a comprehensive list of adverse effects.
Applies to lisinopril: oral extemporaneous suspension, oral tablets.
Side effects include:
Patients with hypertension: Headache, dizziness, cough, fatigue, diarrhea, upper respiratory tract infection, nausea. With fixed combination preparation, muscle cramps, asthenia, orthostatic effects, paresthesia.
Patients with heart failure: Dizziness, hypotension, headache, diarrhea, chest pain, nausea, abdominal pain, rash, upper respiratory tract infection.
Patients with acute MI: Hypotension, renal dysfunction.
For Healthcare Professionals
Applies to lisinopril: oral solution, oral tablet.
Very common (10% or more): Hypotension (11%)
Common (1% to 10%): Chest pain, angina pectoris, orthostatic hypotension, palpitations
Uncommon (0.1% to 1%): Angioneurotic edema, myocardial infarction or cerebrovascular accident, palpitations, tachycardia, Raynaud's phenomenon[Ref]
Hypotension is most likely in patients who are sodium and intravascular volume depleted. In large studies, patients have reported "heart pounding" and chest pain, although the relationship to lisinopril is questionable.[Ref]
Common (1% to 10%): Creatinine increased (10%)
Very rare (less than 0.01%): Renal insufficiency[Ref]
Very common (10% or more): Dizziness (19%)
Common (1% to 10%): Headache, syncope
Uncommon (0.1% to 1%): Paresthesias[Ref]
Common (1% to 10%): Creatinine increased (10%)
Uncommon (0.1% to 1%): Rhinitis
Very rare (less than 0.01%): Bronchospasm, sinusitis, allergic alveolitis/eosinophilic pneumonia[Ref]
A study has revealed a significantly higher incidence of discontinuation of angiotensin converting enzyme inhibitor therapy due to cough among black patients compared with nonblack patients (9.6% vs. 2.4%).[Ref]
Common (1% to 10%): Hyperkalemia
Frequency not reported: Gout, hypoglycemia in diabetic patients receiving ACE inhibitors when concurrently treated with oral antidiabetic agents or insulin[Ref]
Common (1% to 10%): Diarrhea, nausea, vomiting
Frequency not reported: Pancreatitis, constipation, flatulence, dry mouth, taste disturbance[Ref]
Uncommon (0.1% to 1%): Angioedema[Ref]
Uncommon (0.1% to 1%): Rash, pruritus, erythema
Rare (0.01% to 0.1%): Alopecia, urticaria, psoriasis, hypersensitivity/angioedema, angioneurotic edema of the face, extremities, lips, tongue, glottis, and/or larynx
Very rare (less than 0.01%): Sweating, skin lesions, skin infections, pemphigus, toxic epidermal necrolysis, Stevens-Johnson Syndrome, erythema multiforme, cutaneous pseudolymphoma
Frequency not reported: Photosensitivity, flushing, diaphoresis[Ref]
Very rare (less than 0.01%): Bone marrow depression, hemolytic anemia, leukopenia/neutropenia, thrombocytopenia, decreases in hemoglobin, decreases in hematocrit[Ref]
Rare (0.01% to 0.1%): Memory impairment, confusion, somnolence, irritability, nervousness, hallucinations
Very rare (less than 0.01%): Mania
Common (1% to 10%): Creatinine increased
Very rare (less than 0.01%): Cholestatic jaundice that progresses to fulminant hepatic necrosis and sometimes death (discontinue of therapy if jaundice or markedly elevated hepatic serum enzymes develop)
Very rare (less than 0.01%): Diabetes, syndrome of inappropriate antidiuretic hormone secretion (SIADH)
Common (1% to 10%): Cough
Frequency not reported: Fatigue, asthenia, orthostatic effects, tinnitus, olfactory disturbance
Uncommon (0.1% to 1%): Impotence
Rare (less than 0.1%): Gynecomastia
Frequency not reported: Proteinuria
Frequently asked questions
- What is the best time of day to take blood pressure medication?
- How long after taking 5 mg lisinopril will my blood pressure drop down?
- Does lisinopril cause weight gain?
- Do ACE inhibitors make COVID-19 worse?
- Can I just stop taking lisinopril?
- What is the strength of Qbrelis (lisinopril) oral solution?
More about Prinivil (lisinopril)
- Check interactions
- Reviews (11)
- Drug images
- Dosage information
- Patient tips
- During pregnancy
- Drug class: Angiotensin Converting Enzyme Inhibitors
- En español
Related treatment guides
1. "Product Information. Prinivil (lisinopril)." Merck & Co., Inc (2002):
2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
3. Pharmaceutical Society of Australia "APPGuide online. Australian prescription products guide online. http://www.appco.com.au/appguide/default.asp" (2006):
4. Cerner Multum, Inc. "Australian Product Information." O 0
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.