Clobex Side Effects
Generic name: clobetasol topical
Medically reviewed by Drugs.com. Last updated on Feb 16, 2022.
Note: This document contains side effect information about clobetasol topical. Some of the dosage forms listed on this page may not apply to the brand name Clobex.
For the Consumer
Applies to clobetasol topical: topical application cream, topical application emollient cream, topical application foam, topical application gel/jelly, topical application lotion, topical application ointment, topical application shampoo, topical application solution, topical application spray
Side effects requiring immediate medical attention
Along with its needed effects, clobetasol topical (the active ingredient contained in Clobex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking clobetasol topical:
- Burning or stinging at the application site
- Burning sensation of the skin
- dry skin
- flushing or redness of the skin
- itching, scaling, severe redness, soreness, or swelling of the skin
- skin irritation
- skin rash, encrusted, scaly and oozing
- thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (eg, between the fingers)
- Thinning, weakness, or wasting away of the skin
Incidence not known
- blurred vision
- burning, itching, and pain in hairy areas, or pus at the root of the hair
- change in vision
- dry mouth
- eye pain
- facial hair growth in females
- fruit-like breath odor
- full or round face, neck, or trunk
- hair loss
- increased hunger
- increased thirst
- increased urination
- loss of sexual desire or ability
- menstrual irregularities
- muscle wasting
- redness and scaling around the mouth
- stomach pain
- sugar in the urine
- thinning of the hair
- troubled breathing
- unexplained weight loss
- unusual tiredness or weakness
Side effects not requiring immediate medical attention
Some side effects of clobetasol topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- sore throat
- Body aches or pain
- changes in skin coloring
- dryness of the throat
- raised, dark red, wart-like spots on the skin, especially when used on the face
- skin discomfort
- stuffy or runny nose
- tender, swollen glands in the neck
- trouble swallowing
- voice changes
Incidence not known
- Acne or pimples
- burning and itching of the skin with pinhead-sized red blisters
- increased hair growth on the forehead, back, arms, and legs
- lightening of normal skin color
- lightening of treated areas of dark skin
- reddish purple lines on the arms, face, legs, trunk, or groin
- softening of the skin
For Healthcare Professionals
Applies to clobetasol topical: compounding powder, topical cream, topical foam, topical gel, topical kit, topical lotion, topical ointment, topical shampoo, topical solution, topical spray
The most common side effect reported was skin discomfort.[Ref]
Common (1% to 10%): Skin discomfort, acne/folliculitis, telangiectasia, skin atrophy, dry skin
Frequency not reported: Stria, purpura, contact dermatitis, pigmentation changes, pustular eruptions, hypertrichosis, irritant dermatitis
Frequency not reported: Itching[Ref]
Common (1% to 10%): Eye stinging/burning
Postmarketing reports: Eye pain, blurred vision, eye irritation[Ref]
Postmarketing reports: Nausea[Ref]
Frequency not reported: Hyperglycemia, glucosuria[Ref]
Common (1% to 10%): Headache
Frequently asked questions
- Does it help hair growth?
- How often can I use it?
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More about Clobex (clobetasol topical)
- Drug interactions
- Dosage information
- During pregnancy or Breastfeeding
- Reviews (38)
- Patient tips
- Pricing & coupons
- Generic availability
- En español
- Drug class: topical steroids
- Latest FDA Alerts (1)
- Drug Information
- Clobex (Advanced Reading)
- Clobex (Clobetasol Lotion)
- Clobex (Clobetasol Shampoo)
- Clobex (Clobetasol Spray)
Related treatment guides
1. "Product Information. Temovate (clobetasol)." Glaxo Wellcome, Research Triangle Park, NC.
2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
3. Cerner Multum, Inc. "Australian Product Information." O 0
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.