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How often can I use Clobex?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on Nov 30, 2020.

Official Answer

by Drugs.com

Clobex (clobetasol propionate) is a super-high potent topical (used on the skin) corticosteroid available as a spray, lotion and shampoo. Use Clobex Lotion exactly as your doctor tells you to use it.

Clobex Spray 0.05%: Spray directly on to the affected skin area twice a day and rub in gently.

  • If no improvement is seen within 2 weeks, contact your doctor.
  • Do not use more than 26 sprays per application or 52 sprays per day.
  • Do not apply more than 59 mL (2 fluid ounces) of Clobex Spray 0.05% to your skin in one week.
  • Clobex Spray should not be used in the treatment of rosacea or perioral dermatitis.

Clobex Lotion 0.05%: Apply directly on to the affected skin area twice a day and rub in gently.

  • Do not apply more than 50 mL (1.75 fluid ounces) of Clobex Lotion 0.05% to your skin in one week.
  • Clobex Lotion 0.05% should not be used for more than 2 weeks in a row unless your doctor tells you to use it for a longer time.

Clobex Shampoo 0.05%: Apply onto a dry (not wet) scalp once a day.

  • Apply as a thin film to the affected areas only, and leave in place for 15 minutes before lathering and rinsing.
  • For use on the scalp only. Do not wet your hair before using Clobex Shampoo.
  • Do not use more than 50 mL (1.75 fluid ounce) per week of Clobex Shampoo, 0.05%.
  • Tell your doctor if your scalp condition is not getting better after four weeks of using Clobex Shampoo.

Clobex (clobetasol propionate) 0.05% is a super-high potent topical corticosteroid available as a spray, lotion and shampoo. Clobex Spray is used to treat plaque psoriasis on the skin and Clobex Shampoo is used for scalp psoriasis. Clobex Lotion is approved to treat the redness, swelling and itching associated with certain skin conditions (known as corticosteroid-responsive dermatoses), such as atopic dermatitis (eczema) and plaque psoriasis.

Clobex is only for topical use in people 18 years of age and older. Do not exceed the dose that your doctor prescribes due to a risk of hypothalamic-pituitary-adrenal (HPA) axis suppression. HPA axis suppression can lead to side effects such as high blood sugar, unmasking of diabetes, and Cushing's syndrome, among others.

Clobex should not be used on the face, groin or axillae (underarms). Keep out of the eyes and away from the lips. Use only in the affected area, and rinse fully with water if Clobex should get in area other than the treatment area.

Bottom Line

  • Clobex Spray 0.05% and Clobex Lotion 0.05% are both applied to the affected skin area twice a day and rubbed in gently. Do not use longer than 2 weeks unless directed to do so by your doctor.
  • Clobex Shampoo 0.05% is applied as a thin film to the affected scalp area once per day. Apply only to dry scalp (not wet). Leave in place for 15 minutes before lathering and rinsing. Tell your doctor if your scalp psoriasis is not getting better after using Clobex Shampoo for 4 weeks.

This is not all the information you need to know about Clobex (clobetasol propionate 0.05%) Topical Spray, lotion or shampoo for safe and effective use. Review the full Clobex information, and discuss this information and any questions you have with your doctor or other health care provider.

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