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What's difference between Olux and Olux-E?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on Dec 2, 2020.

Official Answer

by Drugs.com

Key Points

Olux and Olux-E are topically applied (on the skin) corticosteroid foams that contain clobetasol propionate 0.05%, but they are approved for different uses.

  • Olux is approved to treat plaque psoriasis of the scalp and other nonscalp areas on the body, except the face and areas where the skin may touch or rub together (intertriginous areas).
  • Olux-E is approved to treat the swelling and itching of skin conditions that respond to topical corticosteroids (for example: psoriasis, seborrheic dermatitis, eczema, skin rash or skin allergy). Olux-E is formulated as an emulsion aerosol foam mixture with moisturizing properties.
  • Both products are used only in patients 12 years of age and older.

The brand name products Olux and Olux-E are manufactured by Mylan Pharmaceuticals. Both agents are available as a generic option.

What is in Olux and Olux-E?

Clobetasol propionate 0.05% is the active ingredient in both Olux foam and Olux-E foam. Clobetasol is classified as a super-high potent topical corticosteroid, used to treat certain skin conditions to help relieve redness, swelling, itching and scaling.

Is the dose the same for Olux and Olux-E?

Always use Olux and Olux-E Foam exactly as your healthcare provider tells you to use it.

The dosage for Olux and the dosage for Olux-E are similar. Both products are applied twice a day, usually once in the morning and once in the evening.

  • Do not use more than 50 grams per week or more than 21 capfuls per week. Do not use it for longer than 2 weeks in a row.
  • Talk to your healthcare provider if your treated area does not improve after 2 weeks of treatment.

Avoid using Olux or Olux-E on your face, underarms, groin area, or in areas with thinning skin (atrophy). Do not use these products with an occlusive dressing (such as a bandage or patch) unless directed by your physician. Do not get these products in your eyes, mouth, or vagina; if contact happens, rinse well with water.

Follow the Instructions for Use found in the package inserts for Olux and Olux-E.

Bottom Line

  • Olux and Olux-E are both topical corticosteroid foams that contain clobetasol propionate 0.05%, but they are approved for somewhat different uses. They are approved for use in patients 12 years of age and older.
  • Olux is approved to treat plaque psoriasis of the scalp and other areas on the body, except the face and areas where the skin may touch or rub together (intertriginous areas).
  • Olux-E is approved to treat the swelling and itching of skin conditions that respond to topical corticosteroids (for example: psoriasis, seborrheic dermatitis, eczema, skin rash or skin allergy). Olux-E is formulated as an emulsion aerosol foam mixture.

This is not all the information you need to know about Olux and Olux-E (clobetasol propionate 0.05% foam) for safe and effective use. Review the full Olux and Olux-E product information, including additional warnings and side effects, and discuss this information and any questions you have with your doctor or other health care provider.

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