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Ansaid Side Effects

Generic name: flurbiprofen

Medically reviewed by Last updated on Jul 30, 2023.

Note: This document contains side effect information about flurbiprofen. Some dosage forms listed on this page may not apply to the brand name Ansaid.

Applies to flurbiprofen: oral tablet.


Oral route (Tablet)

NSAIDs cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use. Flurbiprofen is contraindicated in the setting of CABG surgery. NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events.

Serious side effects of Ansaid

Along with its needed effects, flurbiprofen (the active ingredient contained in Ansaid) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking flurbiprofen:

Less common


Get emergency help immediately if any of the following symptoms of overdose occur while taking flurbiprofen:

Symptom of overdose

Other side effects of Ansaid

Some side effects of flurbiprofen may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common


For Healthcare Professionals

Applies to flurbiprofen: compounding powder, oral tablet.


The most frequently reported side effects were gastrointestinal (GI) in nature and included abdominal pain, constipation, diarrhea, dyspepsia/heartburn, flatulence, GI bleeding, nausea, and vomiting.[Ref]


Common (1% to 10%): Abdominal pain, constipation, diarrhea, dyspepsia/heartburn, flatulence, GI bleeding, nausea, vomiting

Frequency not reported: Bloody diarrhea, esophageal disease, gastric/peptic ulcer disease, gastritis, hematemesis, stomatitis, glossitis, colitis, dry mouth, exacerbation of inflammatory bowel disease, exacerbation of Crohn's disease, exacerbation of ulcerative colitis, small intestine inflammation with blood and protein loss, GI perforation, duodenal ulcer, pancreatitis, ulcerative stomatitis[Ref]

Nervous system

Common (1% to 10%): Headache, reflexes increased, tremor, central nervous system (CNS) stimulation, CNS inhibition, amnesia, somnolence

Frequency not reported: Ataxia, cerebrovascular ischemia, paresthesia, convulsion, cerebrovascular accident, hypertonia, subarachnoid hemorrhage, dizziness/vertigo, parosmia, taste changed, retrobulbar neuritis, optic neuritis[Ref]


Common (1% to 10%): Edema, asthenia, malaise, tinnitus

Frequency not reported: Chills, fever, periodontal abscess, meningitis, aseptic meningitis, herpes simples, herpes zoster, ear disease, transient hearing loss, fatigue[Ref]


Common (1% to 10%): Rhinitis

Frequency not reported: Asthma, epistaxis, bronchitis, dyspnea, hyperventilation, laryngitis, pulmonary embolism, pulmonary infarct, bronchospasm[Ref]


Common (1% to 10%): Elevated liver enzymes

Frequency not reported: Cholestatic jaundice, noncholestatic jaundice, hepatitis, cholecystitis, liver failure, abnormal liver function[Ref]


Frequency not reported: Interstitial nephritis, renal failure, nephrotic syndrome[Ref]


Common (1% to 10%): Rash

Frequency not reported: Ecchymosis, purpura, angioedema, eczema, exfoliative dermatitis, photosensitivity, pruritus, toxic epidermal necrolysis, urticaria, alopecia, dry skin, nail disorder, sweating, bullous dermatoses, Stevens-Johnson syndrome, erythema multiforme[Ref]


Common (1% to 10%): Vision changes

Frequency not reported: Conjunctivitis, corneal opacity, glaucoma, retinal hemorrhage, visual disturbance[Ref]


Common (1% to 10%): Nervousness, anxiety, insomnia, depression

Frequency not reported: Confusion, emotional lability, hallucinations[Ref]


Frequency not reported: Hypersensitivity reaction[Ref]


Frequency not reported: Aplastic anemia, agranulocytosis, pancytopenia, hemoglobin decreased, hematocrit decreased, eosinophilia, hemolytic anemia, iron deficiency anemia, leukopenia, thrombocytopenia, lymphadenopathy, anemia, bleeding time increased, neutropenia[Ref]


Frequency not reported: Congestive heart failure, hypertension, vascular diseases, vasodilation, angina pectoris, arrhythmias, myocardial infarction, cardiac failure[Ref]


Common (1% to 10%): Urinary tract infection

Frequency not reported: Hematuria, menstrual disturbances, vaginal hemorrhage, uterine hemorrhage, vulvovaginitis, prostate disease[Ref]


Frequency not reported: Anaphylactic reaction[Ref]


Common (1% to 10%): Body weight changes

Frequency not reported: Appetite changes, hyperuricemia, hyperkalemia[Ref]


Frequency not reported: Twitching, myasthenia[Ref]

Frequently asked questions


1. (2001) "Product Information. Ansaid (flurbiprofen)." Pharmacia and Upjohn

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

3. Cerner Multum, Inc. "Australian Product Information."

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.