Drug Interactions between gabapentin and Unasyn
This report displays the potential drug interactions for the following 2 drugs:
- gabapentin
- Unasyn (ampicillin/sulbactam)
Interactions between your drugs
No interactions were found between gabapentin and Unasyn. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
gabapentin
A total of 271 drugs are known to interact with gabapentin.
- Gabapentin is in the drug class gamma-aminobutyric acid analogs.
-
Gabapentin is used to treat the following conditions:
- Alcohol Use Disorder (off-label)
- Alcohol Withdrawal (off-label)
- Anxiety (off-label)
- Back Pain
- Benign Essential Tremor (off-label)
- Bipolar Disorder (off-label)
- Burning Mouth Syndrome (off-label)
- Carpal Tunnel Syndrome (off-label)
- Chronic Kidney Disease-Associated Pruritus (off-label)
- Chronic Pain
- Cluster-Tic Syndrome (off-label)
- Cough (off-label)
- Diabetic Peripheral Neuropathy (off-label)
- Epilepsy
- Erythromelalgia (off-label)
- Fibromyalgia (off-label)
- Hiccups (off-label)
- Hot Flashes (off-label)
- Hyperhidrosis (off-label)
- Insomnia (off-label)
- Lhermitte's Sign (off-label)
- Migraine (off-label)
- Nausea/Vomiting, Chemotherapy Induced (off-label)
- Neuropathic Pain (off-label)
- Occipital Neuralgia (off-label)
- Pain (off-label)
- Periodic Limb Movement Disorder (off-label)
- Peripheral Neuropathy (off-label)
- Postherpetic Neuralgia
- Postmenopausal Symptoms (off-label)
- Primary Orthostatic Tremor (off-label)
- Pruritus (off-label)
- Pudendal Neuralgia (off-label)
- Reflex Sympathetic Dystrophy Syndrome (off-label)
- Restless Legs Syndrome (off-label)
- Seizures
- Small Fiber Neuropathy (off-label)
- Spondylolisthesis (off-label)
- Syringomyelia (off-label)
- Transverse Myelitis (off-label)
- Trigeminal Neuralgia (off-label)
- Vulvodynia (off-label)
Unasyn
A total of 81 drugs are known to interact with Unasyn.
- Unasyn is in the drug class penicillins/beta-lactamase inhibitors.
-
Unasyn is used to treat the following conditions:
- Aspiration Pneumonia
- Bacterial Infection
- Bone infection
- Deep Neck Infection
- Endocarditis
- Epiglottitis
- Intraabdominal Infection
- Joint Infection
- Kidney Infections
- Meningitis
- Pelvic Inflammatory Disease
- Peritonitis
- Pneumonia
- Sinusitis
- Skin and Structure Infection
- Skin or Soft Tissue Infection
- Surgical Prophylaxis
- Urinary Tract Infection
Drug and food/lifestyle interactions
ampicillin food/lifestyle
Applies to: Unasyn (ampicillin / sulbactam)
ADJUST DOSING INTERVAL: Certain penicillins may exhibit reduced gastrointestinal absorption in the presence of food. The therapeutic effect of the antimicrobial may be reduced.
MANAGEMENT: The interacting penicillin should be administered one hour before or two hours after meals. Penicillin V and amoxicillin are not affected by food and may be given without regard to meals.
References (6)
- Neu HC (1974) "Antimicrobial activity and human pharmacology of amoxicillin." J Infect Dis, 129, s123-31
- Welling PG, Huang H, Koch PA, Madsen PO (1977) "Bioavailability of ampicillin and amoxicillin in fasted and nonfasted subjects." J Pharm Sci, 66, p. 549-52
- McCarthy CG, Finland M (1960) "Absorption and excretion of four penicillins." N Engl J Med, 263, p. 315-26
- Cronk GA, Wheatley WB, Fellers GF, Albright H (1960) "The relationship of food intake to the absorption of potassium alpha-phenoxyethyl penicillin and potassium phenoxymethyl penicillin from the gastrointestinal tract." Am J Med Sci, 240, p. 219-25
- Klein JO, Sabath LD, Finland M (1963) "Laboratory studies on oxacillin. I: in vitro activity against staphylococci and some other bacterial pathogens. II: absorption and urinary excretion in normal young." Am J Med Sci, 245, p. 399-411
- Neuvonen PJ, Elonen E, Pentikainen PJ (1977) "Comparative effect of food on absorption of ampicillin and pivampicillin." J Int Med Res, 5, p. 71-6
gabapentin food/lifestyle
Applies to: gabapentin
GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol. Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
References (4)
- Warrington SJ, Ankier SI, Turner P (1986) "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology, 15, p. 31-7
- Gilman AG, eds., Nies AS, Rall TW, Taylor P (1990) "Goodman and Gilman's the Pharmacological Basis of Therapeutics." New York, NY: Pergamon Press Inc.
- (2012) "Product Information. Fycompa (perampanel)." Eisai Inc
- (2015) "Product Information. Rexulti (brexpiprazole)." Otsuka American Pharmaceuticals Inc
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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