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Unasyn (ampicillin / sulbactam) Drug Interactions

A total of 83 drugs are known to interact with Unasyn (ampicillin / sulbactam).

  • 3 major drug interactions
  • 63 moderate drug interactions
  • 17 minor drug interactions

Show all medications in the database that may interact with Unasyn (ampicillin / sulbactam).

Check for interactions

Type in a drug name to check for interactions with Unasyn (ampicillin / sulbactam).

Most frequently checked interactions

View interaction reports for Unasyn (ampicillin / sulbactam) and the medicines listed below.

  • acetylcysteine (Mucomyst, NAC, Mucomyst-10, Acetadote, Cetylev, Mucomyst-20, Solgar NAC, Acys-5, Parvolex)
  • amlodipine (Norvasc)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Ascriptin, Bufferin, Fasprin, Arthritis Pain, Easprin, Aspergum, Aspiritab, Halfprin, Empirin, Ascriptin Enteric, Aspirin Lite Coat, Aspi-Cor, Aspirtab, Ecotrin Adult Low Strength, Bayer Children's Aspirin, Buffered Aspirin, Durlaza, Entercote, St. Joseph Aspirin, Acuprin 81, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Migralex, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Bufferin Low Dose, Medi-Seltzer, Sloprin, St. Joseph 81 mg Chewable Aspirin, ZORprin, Low Dose ASA, Bayer Aspirin Extra Strength Plus, Buffex, Ecotrin Maximum Strength, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Ecpirin, Bayer Women's Aspirin With Calcium, Zero-Order Release, YSP Aspirin, Miniprin, Bayer Aspirin Regimen, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Augmentin (amoxicillin / clavulanate)
  • azithromycin (Zithromax, Azithromycin Dose Pack, Z-Pak, Zmax)
  • cefepime (Maxipime)
  • ceftriaxone (Rocephin)
  • clindamycin (Cleocin, Cleocin Phosphate, Cleocin Pediatric, Cleocin HCl, Cleocin Phosphate ADD-Vantage)
  • fluconazole (Diflucan)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Children's Motrin, Proprinal, Motrin IB, Childrens Ibuprofen Berry, Advil Children's, Ibuprofen PMR, Ibu-8, Rufen, IBU-200, Motrin Childrens, Advil Migraine, Caldolor, Ibu-Tab, Menadol, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Pediatric, Genpril, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, Addaprin, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, Motrin Junior Strength, Motrin Infant Drops, NeoProfen, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • Lasix (furosemide)
  • morphine (MS Contin, Morphine Sulfate ER, Morphine Sulfate IR, Roxanol, Kadian, MorphaBond ER, Duramorph, MSIR, Statex, Morphine Sulfate SR, Avinza, Arymo ER, M-Eslon, Astramorph PF, Oramorph SR, Morphine Rapi-Ject, Infumorph, Morphine LP Epidural, RMS, Mitigo, Duramorph PF, OMS, Roxanol 100, Rescudose, MS/S, Roxanol-T, Doloral, Doloral Sirop, Morphitec, M O S)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • Percocet (acetaminophen / oxycodone)
  • prednisone (Deltasone, Rayos, Sterapred, Prednicot, Meticorten, Sterapred DS, Liquid Pred, Orasone, Prednicen-M)
  • Protonix (pantoprazole)
  • Rocephin (ceftriaxone)
  • simvastatin (Zocor, FloLipid)
  • vancomycin (Vancocin, Firvanq, Vancocin HCl, Lyphocin, Vancocin HCl Pulvules)
  • Zofran (ondansetron)
  • Zosyn (piperacillin / tazobactam)

Unasyn (ampicillin / sulbactam) alcohol/food interactions

There are 2 alcohol/food interactions with Unasyn (ampicillin / sulbactam)

Unasyn (ampicillin / sulbactam) disease interactions

There are 5 disease interactions with Unasyn (ampicillin / sulbactam) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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