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Drug Interactions between Unasyn and vancomycin

This report displays the potential drug interactions for the following 2 drugs:

  • Unasyn (ampicillin/sulbactam)
  • vancomycin

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Interactions between your drugs

No interactions were found between Unasyn and vancomycin. This does not necessarily mean no interactions exist. Always consult your healthcare provider.


A total of 50 drugs are known to interact with Unasyn.


A total of 122 drugs are known to interact with vancomycin.

Drug and food interactions


ampicillin food

Applies to: Unasyn (ampicillin / sulbactam)

You may experience reduced absorption of ampicillin in the presence of food. The effectiveness of the antibiotic may be reduced. Ampicillin should be administered one hour before or two hours after meals. This will make it easier for your body to absorb the medication. Penicillin V and amoxicillin are not affected by food and may be given without regard to meals.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.