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Medications for Interstitial Cystitis

Other names: Cystitis, Interstitial

What is Interstitial Cystitis:  Interstitial cystitis is noninfectious bladder inflammation that causes pain and urinary frequency and urgency with incontinence.

Medications to treat Interstitial Cystitis

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Elmiron B N 63 reviews
7.0

Generic name: pentosan polysulfate sodium systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
phenazopyridine B N 31 reviews
8.0

Generic name: phenazopyridine systemic

Brand names:  Pyridium, Azo-Standard, Uristat, Azo Urinary Pain Relief, Uricalm, Baridium, Azo-Gesic, Prodium, Pyridiate, Azo-Septic, Re-Azo

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Pyridium B N 8 reviews
7.0

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
amitriptyline C N X 44 reviews
8.0

Generic name: amitriptyline systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Sanctura Off Label C N X 1 review
10

Generic name: trospium systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
hydroxyzine Off Label N N X 3 reviews
6.0

Generic name: hydroxyzine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Azo-Standard B N 3 reviews
9.0

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Tofranil N N X 1 review
9.0

Generic name: imipramine systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Uristat B N 3 reviews
9.0

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Sanctura XR Off Label C N X 1 review
10

Generic name: trospium systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Azo Urinary Pain Relief B N 3 reviews
6.0

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
pentosan polysulfate sodium B N 67 reviews
7.0

Generic name: pentosan polysulfate sodium systemic

Brand name:  Elmiron

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
trospium Off Label C N X 2 reviews
10

Generic name: trospium systemic

Brand names:  Sanctura, Sanctura XR

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Uricalm B N Add review Rate

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
imipramine N N X 1 review
9.0

Generic name: imipramine systemic

Brand names:  Tofranil, Tofranil-PM

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Rimso-50 C N Add review Rate

Generic name: dimethyl sulfoxide systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Baridium B N Add review Rate

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Azo-Gesic B N Add review Rate

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
dimethyl sulfoxide C N Add review Rate

Generic name: dimethyl sulfoxide systemic

Brand names:  Rimso-50, Cryoserv

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Prodium B N Add review Rate

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Pyridiate B N Add review Rate

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Tofranil-PM N N X Add review Rate

Generic name: imipramine systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Azo-Septic B N Add review Rate

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Cryoserv C N Add review Rate

Generic name: dimethyl sulfoxide systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Re-Azo B N Add review Rate

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 

Learn more about Interstitial Cystitis

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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