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Medications for Interstitial Cystitis

Other names: Cystitis, Interstitial

About Interstitial Cystitis:  Interstitial cystitis is noninfectious bladder inflammation that causes pain and urinary frequency and urgency with incontinence.

Drugs Used to Treat Interstitial Cystitis

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Elmiron B N 86 reviews
7.4

Generic name: pentosan polysulfate sodium systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

phenazopyridine B N 39 reviews
7.6

Generic name: phenazopyridine systemic

Brand names:  Pyridium, Uristat, Azo-Standard, Azo Urinary Pain Relief, Uricalm, Baridium, Azo-Gesic, Prodium, Azo-Septic, Re-Azo …show all

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

amitriptyline C N X 59 reviews
8.2

Generic name: amitriptyline systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Pyridium B N 8 reviews
7.3

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

hydroxyzine Off Label N N X 4 reviews
6.4

Generic name: hydroxyzine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

pentosan polysulfate sodium B N 91 reviews
7.5

Generic name: pentosan polysulfate sodium systemic

Brand name:  Elmiron

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Uristat B N 3 reviews
9.0

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

Azo-Standard B N 5 reviews
8.8

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

Tofranil N N X 1 review
9.0

Generic name: imipramine systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

trospium Off Label C N X 2 reviews
10

Generic name: trospium systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Azo Urinary Pain Relief B N 5 reviews
4.8

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

imipramine N N X 1 review
9.0

Generic name: imipramine systemic

Brand names:  Tofranil, Tofranil-PM

Drug class: tricyclic antidepressants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Uricalm B N Add review
0.0

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

Baridium B N Add review
0.0

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

dimethyl sulfoxide C N Add review
0.0

Generic name: dimethyl sulfoxide systemic

Brand names:  Rimso-50, Cryoserv

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions,

Rimso-50 C N Add review
0.0

Generic name: dimethyl sulfoxide systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Azo-Gesic B N Add review
0.0

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Prodium B N Add review
0.0

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

Tofranil-PM N N X Add review
0.0

Generic name: imipramine systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Azo-Septic B N Add review
0.0

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

Cryoserv C N Add review
0.0

Generic name: dimethyl sulfoxide systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

Re-Azo B N Add review
0.0

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

Learn more about Interstitial Cystitis

IBM Watson Micromedex

Symptoms and treatments

Mayo Clinic Reference

ICD-10 CM Clinical Codes (External)

Legend

Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Off Label This medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

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