Skip to Content

Medications for Interstitial Cystitis

Drugs associated with Interstitial Cystitis

The following drugs and medications are in some way related to, or used in the treatment of this condition.

What is Interstitial Cystitis: Interstitial cystitis is noninfectious bladder inflammation that causes pain and urinary frequency and urgency with incontinence.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Elmiron Rx B N 43 reviews
7.0

Generic name: pentosan polysulfate sodium systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Pyridium Rx/OTC B N 8 reviews
7.0

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
amitriptyline Rx C N X 35 reviews
8.0

Generic name: amitriptyline systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
phenazopyridine Rx/OTC B N 27 reviews
8.0

Generic name: phenazopyridine systemic

Brand names:  Pyridium, Azo-Standard, Uristat, Azo Urinary Pain Relief, Uricalm, Baridium, Azo-Gesic, Azo-Septic, Prodium, Pyridiate, Re-Azo

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Sanctura Off Label Rx C N X 1 review
10

Generic name: trospium systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
hydroxyzine Off Label Rx N N X 1 review
7.0

Generic name: hydroxyzine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Azo-Standard Rx/OTC B N 3 reviews
9.0

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Tofranil Rx N N X 1 review
9.0

Generic name: imipramine systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Sanctura XR Off Label Rx C N X 1 review
10

Generic name: trospium systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Uristat Rx/OTC B N 3 reviews
9.0

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Azo Urinary Pain Relief Rx/OTC B N 3 reviews
6.0

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
pentosan polysulfate sodium Rx B N 47 reviews
7.0

Generic name: pentosan polysulfate sodium systemic

Brand name:  Elmiron

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
trospium Off Label Rx C N X 2 reviews
10

Generic name: trospium systemic

Brand names:  Sanctura, Sanctura XR

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Uricalm Rx/OTC B N Add review Add

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
imipramine Rx N N X 1 review
9.0

Generic name: imipramine systemic

Brand names:  Tofranil, Tofranil-PM

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Baridium Rx/OTC B N Add review Add

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Rimso-50 Rx C N Add review Add

Generic name: dimethyl sulfoxide systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Azo-Gesic Rx/OTC B N Add review Add

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
dimethyl sulfoxide Rx C N Add review Add

Generic name: dimethyl sulfoxide systemic

Brand names:  Rimso-50, Cryoserv

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Tofranil-PM Rx N N X Add review Add

Generic name: imipramine systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Azo-Septic Rx/OTC B N Add review Add

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Cryoserv Rx C N Add review Add

Generic name: dimethyl sulfoxide systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Prodium Rx/OTC B N Add review Add

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Pyridiate Rx/OTC B N Add review Add

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Re-Azo Rx/OTC B N Add review Add

Generic name: phenazopyridine systemic

Drug class: miscellaneous genitourinary tract agents

For consumers: dosage, interactions, side effects

 
Showing all

Learn more about Interstitial Cystitis

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N The drug is not subject to the Controlled Substances Act.
1 The drug has a high potential for abuse. The drug has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use of the drug under medical supervision.
2 The drug has a high potential for abuse. The drug has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug may lead to severe psychological or physical dependence.
3 The drug has a potential for abuse less than the drugs in schedules 1 and 2. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to moderate or low physical dependence or high psychological dependence.
4 The drug has a low potential for abuse relative to the drugs in schedule 3. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 3.
5 The drug has a low potential for abuse relative to the drugs in schedule 4. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 4.
Alcohol
X Interacts with Alcohol.

Synonym(s): Cystitis, Interstitial

Browse Drugs by Condition

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Hide