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Rimso-50 Side Effects

Generic Name: dimethyl sulfoxide

Note: This document contains side effect information about dimethyl sulfoxide. Some of the dosage forms listed on this page may not apply to the brand name Rimso-50.

For the Consumer

Applies to dimethyl sulfoxide: intravesical solution

Along with its needed effects, dimethyl sulfoxide (the active ingredient contained in Rimso-50) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking dimethyl sulfoxide:

Some patients may have some discomfort during the time this medicine is being put into the bladder. However, the discomfort usually becomes less each time the medicine is used.

Dimethyl sulfoxide may cause you to have a garlic-like taste within a few minutes after the medicine is put into the bladder. This effect may last for several hours. It may also cause your breath and skin to have a garlic-like odor, which may last up to 72 hours.

For Healthcare Professionals

Applies to dimethyl sulfoxide: compounding liquid, irrigation solution, topical solution


Frequency not reported: Odor on skin (may remain for 72 hours)[Ref]


Frequency not reported: Garlic-like taste (a few minutes after instillation), odor on breath (may remain for 72 hours)[Ref]


Frequency not reported: Chemical cystitis[Ref]


Frequency not reported: Severe discomfort on administration[Ref]


1. "Product Information. Rimso-50 (dimethyl sulfoxide)." Edwards Lifesciences, Irvine, CA.

Some side effects of Rimso-50 may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.