Phenazopyridine Side Effects
Medically reviewed by Drugs.com. Last updated on Sep 10, 2023.
Applies to phenazopyridine: oral tablet.
Precautions
Check with your doctor if symptoms such as bloody urine, difficult or painful urination, frequent urge to urinate, or sudden decrease in the amount of urine appear or become worse while you are taking this medicine .
Phenazopyridine causes the urine to turn reddish orange . This is to be expected while you are using it. This effect is harmless and will go away after you stop taking the medicine. Also, the medicine may stain clothing.
For patients who wear soft contact lenses:
- It is best not to wear soft contact lenses while being treated with this medicine. Phenazopyridine may cause discoloration or staining of contact lenses. It may not be possible to remove the stain.
For diabetic patients:
- This medicine may cause false test results with urine sugar tests and urine ketone tests. If you have any questions about this, check with your health care professional, especially if your diabetes is not well controlled.
Before you have any medical tests, tell the person in charge that you are taking this medicine. The results of some tests may be affected by this medicine.
Serious side effects of phenazopyridine
Along with its needed effects, phenazopyridine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur while taking phenazopyridine:
Rare side effects
- blue or blue-purple color of skin
- fever and confusion
- shortness of breath, tightness in chest, wheezing, or troubled breathing
- skin rash
- sudden decrease in the amount of urine
- swelling of face, fingers, feet, and/or lower legs
- unusual tiredness or weakness
- weight gain
- yellow eyes or skin
Other side effects of phenazopyridine
Some side effects of phenazopyridine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common or rare side effects
For healthcare professionals
Applies to phenazopyridine: compounding powder, oral tablet.
Nervous system adverse events
- Frequency not reported: Headache[Ref]
Dermatologic
Gastrointestinal
- Frequency not reported: Upset stomach[Ref]
Genitourinary
- Frequency not reported: Orange to red discoloration of the urine[Ref]
Hypersensitivity
- Frequency not reported: Anaphylactic-like reaction[Ref]
Ocular
- Frequency not reported: Staining of contact lenses[Ref]
See also:
Pyridium
Pyridium (phenazopyridine) treats pain, burning, increased urination, and increased urge to ...
Ditropan
Ditropan XL (oxybutynin extended release) is used to treat the symptoms of overactive bladder ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Tofranil
Tofranil is used for depression, enuresis, pain, primary nocturnal enuresis
Urispas
Urispas is used for dysuria, urinary frequency, urinary incontinence
Ditropan XL
Ditropan XL is used for dysuria, neurogenic detrusor overactivity, urinary frequency, urinary ...
Oxytrol
Oxytrol patches reduces muscle spasms in the urinary tract and are used to treat symptoms of ...
References
1. (2018) "Product Information. Phenazopyridine Hydrochloride (phenazopyridine)." Amneal Pharmaceuticals
2. (2018) "Product Information. AZO Urinary Pain Relief Max Strength (phenazopyridine)." i-Health, Inc
Frequently asked questions
More about phenazopyridine
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (189)
- Drug images
- Dosage information
- During pregnancy
- Support group
- Drug class: miscellaneous genitourinary tract agents
- Breastfeeding
Patient resources
Other brands
Pyridium, Azo Urinary Pain Relief, Uristat, Azo-Standard, ... +8 more
Professional resources
Related treatment guides
Further information
Phenazopyridine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.