Pyridium Side Effects

Generic name: phenazopyridine

Medically reviewed by Drugs.com. Last updated on Sep 10, 2023.

Note: This document provides detailed information about Pyridium Side Effects associated with phenazopyridine. Some dosage forms listed on this page may not apply specifically to the brand name Pyridium.

Applies to phenazopyridine: oral tablet.

Serious side effects of Pyridium

Along with its needed effects, phenazopyridine (the active ingredient contained in Pyridium) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking phenazopyridine:

Rare side effects

• blue or blue-purple color of skin
• fever and confusion
• shortness of breath, tightness in chest, wheezing, or troubled breathing
• skin rash
• sudden decrease in the amount of urine
• swelling of face, fingers, feet, and/or lower legs
• unusual tiredness or weakness
• weight gain
• yellow eyes or skin

Other side effects of Pyridium

Some side effects of phenazopyridine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare side effects

• dizziness
• headache
• indigestion
• itching of the skin
• stomach cramps or pain

For healthcare professionals

Applies to phenazopyridine: compounding powder, oral tablet.

Nervous system adverse events

• Frequency not reported: Headache^[Ref]

Dermatologic

• Frequency not reported: Rash, pruritus^[Ref]

Gastrointestinal

• Frequency not reported: Upset stomach^[Ref]

Genitourinary

• Frequency not reported: Orange to red discoloration of the urine^[Ref]

Hypersensitivity

• Frequency not reported: Anaphylactic-like reaction^[Ref]

Ocular

• Frequency not reported: Staining of contact lenses^[Ref]

Frequently asked questions

• Why do you not take phenazopyridine for more than two days?

Further information

Pyridium side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer