Vortioxetine Alternatives Compared
| Vortioxetine | Rexulti (brexpiprazole) | Vraylar (cariprazine) |
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| Vortioxetine | Rexulti (brexpiprazole) | Vraylar (cariprazine) |
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Prescription only
Vortioxetine may be used to treat depression in adults. It is different from other antidepressants currently on the market because it directly affects serotonin receptors as well as inhibits... View more |
Prescription only
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression, or used to relieve agitation associated with dementia in Alzheimer's disease. Most people... View more |
Prescription only
Vraylar is an atypical antipsychotic that is effective for the treatment of schizophrenia and bipolar I disorder. Vraylar is usually well-tolerated and less likely than some other antipsychotics to... View more |
Related suggestions Major Depressive Disorder
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| More about Vortioxetine | More about Rexulti (brexpiprazole) | More about Vraylar (cariprazine) | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Vortioxetine has an average rating of 6.1 out of 10 from a total of 1567 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 31% reported a negative effect. |
Rexulti has an average rating of 6.6 out of 10 from a total of 492 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 25% reported a negative effect. |
Vraylar has an average rating of 6.1 out of 10 from a total of 524 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 32% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
View all Vortioxetine side effects |
View all Rexulti side effects |
View all Vraylar side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Rexulti prices |
View all Vraylar prices |
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| Dosage Forms | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
| Trintellix |
N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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66 hours |
91 hours |
504 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 355 drugs are known to interact with Vortioxetine:
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A total of 600 drugs are known to interact with Rexulti:
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A total of 577 drugs are known to interact with Vraylar:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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September 30, 2013 |
July 10, 2015 |
September 17, 2015 |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient Resources | ||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Vraylar
Vraylar is a once a day antipsychotic medication used to treat mental health or mood disorders ...
Lexapro
Lexapro is used to treat anxiety and major depressive disorder. Learn about side effects ...
Rexulti
Rexulti (brexpiprazole) is a prescription antipsychotic medication used in the treatment of major ...
Abilify
Abilify is an antipsychotic medicine used to treat the symptoms of schizophrenia and bipolar ...
Zoloft
Zoloft is an antidepressant used to treat major depression, obsessive-compulsive disorder, panic ...
Seroquel
Seroquel is used to treat the symptoms of schizophrenia, bipolar disorder and major depressive ...
Prozac
Prozac (fluoxetine) is an SSRI antidepressant used to treat depression, OCD, panic disorder ...
Cymbalta
Cymbalta (duloxetine) is used to treat major depressive disorder, general anxiety disorder and ...
Wellbutrin
Wellbutrin (bupropion) is used to treat major depressive disorder and seasonal affective disorder ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.