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Vortioxetine Dosage

Medically reviewed by Drugs.com. Last updated on Jun 4, 2024.

Applies to the following strengths: 5 mg; 10 mg; 20 mg

Usual Adult Dose for Depression

Initial dose: 10 mg orally once a day
Maintenance dose: 5 to 20 mg orally once a day
Maximum dose: 20 mg/day

Comments:


Use: Treatment of major depressive disorder (MDD)

Usual Adult Dose for Major Depressive Disorder

Initial dose: 10 mg orally once a day
Maintenance dose: 5 to 20 mg orally once a day
Maximum dose: 20 mg/day

Comments:


Use: Treatment of major depressive disorder (MDD)

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

Switching to/from an MAOI:


CYP450 2D6 Poor Metabolizers: The maximum dose is 10 mg/day

Patients taking Strong Inhibitors of CYP450 2D6:

Patients taking Strong Inducers of CYP450 2D6:

Treatment Discontinuation:

Precautions

US BOXED WARNINGS:
SUICIDAL THOUGHTS AND BEHAVIORS:

Recommendations:

CONTRAINDICATIONS:

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


General:

Monitoring:

Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.