Vortioxetine Disease Interactions
There are 5 disease interactions with vortioxetine:
Antidepressant/antipsychotic agents (applies to vortioxetine) depression
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Bipolar Disorder
Adult and pediatric patients with depression and other psychiatric disorders may experience worsening of their symptoms and may have the emergence of suicidal thoughts and behavior. Patients should be monitored appropriately and observed closely for worsening of their symptoms, suicidality or changes in their behavior, especially during the first few months of treatment, and at times of dose changes. Discontinuing the medication should be considered if symptoms are persistently worse, or abrupt in onset.
Antidepressants (applies to vortioxetine) angle closure glaucoma
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Glaucoma (Narrow Angle)
Some antidepressants exert mydriatic activity that can induce increased intraocular pressure and result in angle-closure (narrow angle) glaucoma in a patient with anatomically narrow angles who does not have a patent iridectomy. Prior to initiating therapy with these agents patients should be examined to determine whether they are susceptible to angle closure, and have a prophylactic procedure (e.g., iridectomy), if they are susceptible. The use of these drugs in patients with untreated anatomically narrow angles should be avoided.
Antidepressants (applies to vortioxetine) bleeding
Moderate Potential Hazard, Moderate plausibility.
Some antidepressants should be administered with caution in patients with an increased risk for hemorrhage. Patients should be advised to immediately report any signs and symptoms suggestive of bleeding complications, including ecchymosis, hematoma, epistaxis, and petechia.
Vortioxetine (applies to vortioxetine) hyponatremia
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Dehydration, SIADH
Treatment with vortioxetine may cause hyponatremia, in many cases secondary to development of the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). Caution should be used when treating patients with hyponatremia or at greater risk of developing hyponatremia such as elderly patients, patients taking diuretics or those who are volume-depleted.
Vortioxetine (applies to vortioxetine) mixed/manic episode
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Depression, Bipolar Disorder, Mania
Therapy with vortioxetine may cause activation of mania and hypomania and should be used with caution in patients with personal or family history of mania, hypomania, bipolar disorder, and other mood disorders.
Vortioxetine drug interactions
There are 330 drug interactions with vortioxetine
Vortioxetine alcohol/food interactions
There is 1 alcohol/food interaction with vortioxetine
More about vortioxetine
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- Drug class: miscellaneous antidepressants
Related treatment guides
Drug Interaction Classification
|No interaction information available.|