Comparing Trintellix vs Venlafaxine
| Trintellix | Venlafaxine |
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| Trintellix (vortioxetine) | Venlafaxine |
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Prescription only
Trintellix may be used to treat depression in adults. It is different from other antidepressants currently on the market because it directly affects serotonin receptors as well as inhibiting... View more |
Prescription only
Venlafaxine is an antidepressant that may also be used for mood disorders and off-label for some other conditions such as hot flashes. It may cause a discontinuation syndrome if abruptly stopped... View more |
Related suggestions Depression
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| More about Trintellix (vortioxetine) | More about Venlafaxine | ||||||||||||||||
| Generic Status | |||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | |||||||||||||||||
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Trintellix has an average rating of 5.9 out of 10 from a total of 1043 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 34% reported a negative effect. |
Venlafaxine has an average rating of 6.4 out of 10 from a total of 2636 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 28% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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Common side effects include:
See also: Trintellix side effects in more detail. |
Commonly reported side effects include:
See also: venlafaxine side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Trintellix prices |
View all venlafaxine prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Effexor, Effexor XR | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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66 hours |
4 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 338 drugs are known to interact with Trintellix:
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A total of 662 drugs are known to interact with venlafaxine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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September 30, 2013 |
December 28, 1993 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.