Comparing Trazodone vs Tylenol PM
| Trazodone | Tylenol PM (acetaminophen / diphenhydramine) |
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| Trazodone | Tylenol PM (acetaminophen / diphenhydramine) |
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Prescription only
Trazodone is mostly used for its sleep-inducing effects (an off-label indication) rather than as an antidepressant. Only generic forms are available which makes it a lot cheaper than some other... View more |
Over-the-counter
Prescribed for Insomnia, Headache, Pain. Tylenol PM may also be used for purposes not listed in this medication guide. |
Related suggestions Insomnia
Headache
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| More about Trazodone | More about Tylenol PM (acetaminophen / diphenhydramine) | ||||||||
| Ratings & Reviews | |||||||||
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Trazodone has an average rating of 6.3 out of 10 from a total of 1436 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. |
Tylenol PM has an average rating of 5.4 out of 10 from a total of 36 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 42% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Trazodone side effects |
View all Tylenol PM side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Trazodone prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Raldesy | Other acetaminophen / diphenhydramine brands include: Acetadryl, Acetaminophen PM Extra Strength, Anacin PM Aspirin Free, Bayer Select Max Strength Night Time Pain, ConRx PM, Counteract PM Extra Strength, Excedrin PM, Genapap PM, Headache Formula PM, Headache Relief PM, Legatrin PM, Mapap PM, Midol PM, Night Time Pain, Non-Aspirin PM Extra Strength, Pain Reliever PM, Percogesic Extra Strength, Percogesic Original Strength, Pharbetol PM, Robitussin Honey Severe Cough, Flu + Sore Throat CF Max Nighttime, Tylenol Sore Throat Nighttime, Unisom PM Pain, Wal-Nadol PM Extra Strength View more | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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7.5 hours |
9.3 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 674 drugs are known to interact with Trazodone:
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A total of 559 drugs are known to interact with Tylenol PM:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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December 24, 1981 |
N/A |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
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N/A |
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| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.