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Tylenol PM (acetaminophen / diphenhydramine) Drug Interactions

A total of 896 drugs (5363 brand and generic names) are known to interact with Tylenol PM (acetaminophen / diphenhydramine).

  • 107 major drug interactions (768 brand and generic names)
  • 752 moderate drug interactions (4230 brand and generic names)
  • 37 minor drug interactions (365 brand and generic names)

Check for interactions with Tylenol PM (acetaminophen / diphenhydramine)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Tylenol PM (acetaminophen / diphenhydramine)

Tylenol PM (acetaminophen / diphenhydramine) alcohol/food Interactions

There is 1 alcohol/food interaction with Tylenol PM (acetaminophen / diphenhydramine)

Tylenol PM (acetaminophen / diphenhydramine) disease Interactions

There are 11 disease interactions with Tylenol PM (acetaminophen / diphenhydramine) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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