Comparing Tramadol vs Duloxetine
| Tramadol | Duloxetine |
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| Tramadol | Duloxetine |
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Prescription only
Tramadol is a strong opioid pain relieving medication that may be used to treat moderate to severe general and nerve-related pain. Tramadol may be habit-forming and misuse can cause addiction... View more |
Prescription only
Duloxetine has antidepressant, anti-anxiety, and pain-relieving properties; however, it may cause a discontinuation syndrome on withdrawal even when tapered. Symptoms may include anxiety, headache... View more |
Related suggestions Depression
Chronic Pain
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| More about Tramadol | More about Duloxetine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Tramadol has an average rating of 7.0 out of 10 from a total of 1877 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 23% reported a negative effect. |
Duloxetine has an average rating of 6.2 out of 10 from a total of 2458 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 31% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Tramadol side effects |
View all Duloxetine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Tramadol prices |
View all Duloxetine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| ConZip, Qdolo, Tramadol Hydrochloride ER | Cymbalta, Drizalma Sprinkle, Irenka | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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5.2 hours |
17 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 712 drugs are known to interact with Tramadol:
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A total of 628 drugs are known to interact with Duloxetine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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March 03, 1995 |
August 03, 2004 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.