Symproic Alternatives Compared
| Symproic (naldemedine) | Movantik (naloxegol) | Amitiza (lubiprostone) |
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| Symproic (naldemedine) | Movantik (naloxegol) | Amitiza (lubiprostone) |
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Prescription only
Prescribed for Opioid-Induced Constipation. Symproic may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Opioid-Induced Constipation, Constipation - Chronic, Constipation - Drug Induced. Movantik may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Irritable Bowel Syndrome with Constipation, Chronic Idiopathic Constipation, Opioid-Induced Constipation, Irritable Bowel Syndrome. Amitiza may also be used for purposes not listed in... View more |
Related suggestions Opioid-Induced Constipation
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| More about Symproic (naldemedine) | More about Movantik (naloxegol) | More about Amitiza (lubiprostone) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Symproic has an average rating of 6.4 out of 10 from a total of 34 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 26% reported a negative effect. |
Movantik has an average rating of 4.9 out of 10 from a total of 265 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 47% reported a negative effect. |
Amitiza has an average rating of 5.6 out of 10 from a total of 270 ratings on Drugs.com. 42% of reviewers reported a positive effect, while 39% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
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View all Symproic side effects |
View all Movantik side effects |
View all Amitiza side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Symproic prices |
View all Movantik prices |
View all Amitiza prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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11 hours |
11 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 179 drugs are known to interact with Symproic:
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A total of 241 drugs are known to interact with Movantik:
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A total of 1 drugs are known to interact with Amitiza:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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March 23, 2017 |
September 16, 2014 |
January 31, 2006 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.