Comparing Spironolactone vs Testosterone

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Spironolactone Remove Spironolactone from your drug comparison	Testosterone Remove Testosterone from your drug comparison	Add another drug to compare

Spironolactone

Testosterone

Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. It does not cause potassium loss from the body; however... View more

Prescribed for Hypogonadism - Male, Delayed Puberty - Male, Postpartum Breast Pain, Breast Cancer - Palliative. May also be prescribed off label for Gender Dysphoria, Klinefelter Syndrome.

Prescription only

Pricing and Coupons

* Prices are without insurance

Quantity	100 each
Dosage	25 mg
Per Unit^*	$0.23
Cost^*	$23.28

View all spironolactone prices

Quantity	75 gram(s)
Dosage	20.25 mg/actuation (1.62%)
Per Unit^*	$1.50
Cost^*	$112.18

View all testosterone prices

Get free Discount Card

Generic Availability

Yes (this medicine)

Dosage Form(s) Available

Oral tablet

Transdermal gel
Transdermal solution

Brand Names

Aldactone, CaroSpir Andro LA 200, Andro-Cyp 100, Andro-Cyp 200, Androderm, AndroGel, Aveed, Delatest, Depandro 100, Depo-Testosterone, Depotest, Duratest, Durathate 200, Everone, FIRST-Testosterone, FIRST-Testosterone MC, Fortesta, Histerone, Jatenzo, Natesto, Striant, Testim, Testo-100, Testopel, Testopel Pellets, Testro-LA, Vogelxo, Xyosted View more

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

37 hours

2 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Moderate abuse potential

Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.

Pregnancy Category

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Category X Not for use in pregnancy

See the full Pregnancy Warnings document.

Drug Interactions

A total of 354 drugs are known to interact with spironolactone:

49 major drug interactions (234 brand and generic names)
282 moderate drug interactions (1339 brand and generic names)
23 minor drug interactions (192 brand and generic names)

A total of 153 drugs are known to interact with testosterone:

12 major drug interactions (53 brand and generic names)
138 moderate drug interactions (562 brand and generic names)
3 minor drug interactions (6 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Spironolactone and alcohol may have additive effects in lowering your blood pressure. You may... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

January 21, 1960

December 24, 1953

WADA Class

View World Anti-Doping Agency classifications.

S5 - Diuretics and Other Masking Agents

S1 - Anabolic Agents

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer