Testosterone and Depression: What Users Say

• Anonymous
• Taken for 1 to 6 months
• June 29, 2013

Testosterone for Hypogonadism, Male "I'm back with AndroGel packet (1 in the morning) after stopping the medication 2 years ago due to elevated liver count and negative side effects. I'm now 50 and was diagnosed at 200 count a few months ago and decided to try it once again. I am no longer dealing with hot flashes, depression, and mood swings - this cured me. However, I have enlarged breasts, slight weight gain, swollen ankles, and not sleeping as well. Back to the Dr. next week to discuss options. Overall satisfied but may need to adjust script somehow."

• New...
• January 7, 2011

Testosterone for Hypogonadism, Male "I'm 49 years old, and my T level was 254. Normal for a 75-year-old, and that's how I felt. No energy, depression, lack of motivation, libido zero. I felt like I had turned into a fat 8-year-old girl. After only 4 days on the AndroGel, I feel better than I have felt in 15 years! Lots of energy, thought processes sharper, motivation has returned. Too soon to tell on the ED symptoms, but otherwise it feels like a miracle. I think I'm getting my life back."

• New...
• January 7, 2011

Testosterone for Hypogonadism, Male "I'm 49 years old, and my T level was 254. Normal for a 75-year-old, and that's how I felt. No energy, depression, lack of motivation, libido zero. I felt like I had turned into a fat 8-year-old girl. After only 4 days on the AndroGel, I feel better than I have felt in 15 years! Lots of energy, thought processes sharper, motivation has returned. Too soon to tell on the ED symptoms, but otherwise it feels like a miracle. I think I'm getting my life back."

• The...
• Taken for 1 to 2 years
• November 17, 2012

Testosterone for Hypogonadism, Male "I've been using AndroGel about a year now. I'm 42, have had zero drive since early 30s. Started me on 8 pumps, now to 9 pumps. I saw someone mention potential effects of depression, it's not helped mine. I also use Cytomel (adjunct depression treatment-however, also hypothyroid). Me no muscle mass/depression/weight loss. The most pronounced effects: *much* firmer erections (like 16 again). That alone is worth it (no need for Cialis). Definitely recommend that alone."

• Sku...
• October 2, 2009

Testosterone for Hypogonadism, Male "I am a 46-year-old male. Memory and tiredness, slight depression. Diagnosed with low testosterone (222 on a scale of 200-800). Have used both Testim and Androgel. Like the way Androgel comes in a pump bottle and is not as sticky as Testim, but my wife and other women have commented that they like the smell of Testim. I now use Testim, applying one tube every other day because my wife says I'm more like myself at that dosage. Had an initial drop of testosterone to 201 when I first started treatment, but testosterone is now at 547 at the last lab. I feel much better."

• ifl...
• Taken for 6 months to 1 year
• February 5, 2016

Testosterone for Hypogonadism, Male "I had ALL (acute lymphoblastic leukemia) then started suffering from having no drive, depression, etc. My Dr. said to try AndroGel 1.62%, which he prescribed. Gradually, I started feeling better. Now, 10 months after starting AndroGel, I no longer suffer the psychological problems, which is a big, big help. This stuff costs so, so much - for 2 bottles of 1.62% pump, it is $985. The price is ridiculous!!"

• Anonymous
• Taken for less than 1 month
• September 3, 2012

Testosterone for Hypogonadism, Male "Been using Testim 1 Gel for 28 days. I'm a 54 y/o, otherwise healthy male who had been experiencing sub-zero sex drive, depression, fatigue, and erectile dysfunction. After four weeks, I've noticed I'm putting on some muscle (but I also spend four days a week at the gym) and I am fantasizing (a lot). Haven't noticed any real improvement in the erectile dysfunction arena, but I maintain the erection I do have quite a bit longer. I believe I'm making progress, but I'd like to see more! By the way, women love this smell...at least the dozen or more who've commented on it to me, anyway. My original 'T' score was 208, and I get tested again next month and will be interested in seeing the degree of change."

• and...
• April 30, 2013

Testosterone for Hypogonadism, Male "At 54, I had little energy by day's end. I was falling asleep in a chair after dinner. For the first time ever, my libido was diminished. I was moody and depressed. I also had problems concentrating at work. On 60 mg for a month, all symptoms turned around except libido. My doctor moved me to 90 mg. I have been on that dosage for 2 weeks and seem to have regular headaches."

• bcw...
• Taken for 1 to 6 months
• August 27, 2012

Testosterone for Hypogonadism, Male "For about 8 months or so, I had started to feel completely different than I had ever felt in life. Now at 53 years old, I don't expect to feel like 20, but I sure didn't want to feel dead either. No interest in things, no libido at all, depressed, moody, and didn't care. I had no energy... none! My first thought was it was thyroid related since I suffer from hypothyroidism and just thought the meds needed to be changed. My doctor and I discussed it, took the various blood tests, etc. The thyroid was fine, but my testosterone levels had fallen almost 200 points since the previous test about a year ago. So, my doc put me on a one-month trial of Axiron, and what a difference. Numbers up 100, no more complaints!"

• Ken...
• Taken for 1 to 6 months
• June 7, 2015

Testosterone for Hypogonadism, Male "I am a two-time testicular cancer survivor. My body no longer produces testosterone. I am 30 years old, and this will be for the rest of my life. I was on Androgel for about two and a half years. The last, I would say, eight months, I felt like complete crap. Depression and always tired and lethargic. Didn't feel like doing anything. No motivation for anything. I just had my second round of Testopel about a week and a half ago, and I love it. The first time I got it, I felt the difference within the first week. Same with this second go-round. I have more energy. The only problem I have is that on both times my incision site leaks, and one pellet did fall out. Other than that, I love this stuff."

• KYB...
• Taken for less than 1 month
• December 3, 2016

Testosterone for Hypogonadism, Male "OK guys, time out! I never thought I'd come to the defense of a consumer product, much less one that costs such an obscene amount of money, but: 1. There are a lot of guys on here complaining they had low testosterone (Low T) and giving their numbers before treatment. A large portion of them say Axiron took their numbers up into the 500 range. THIS IS WHAT THE DRUG IS SUPPOSED TO DO! If you're roughly between 348-1000, you're back to normal. Axiron worked. The fact that you still feel tired, or fatigued, or depressed is most likely due to other issues. I think there are too many guys on here expecting to take this drug and it to turn them into the Hulk, make them happy all the time, and provide for them sex whenever they want it."

• mus...
• June 4, 2011

For Hypogonadism, Male "I was diagnosed with hypogonadism (low testosterone) about ten years ago and started Androgel. I had no problem keeping my testosterone level in the normal range with the Androgel, but it never made me feel better, i.e., no libido, low energy, depression. When I switched to Testosterone Cypionate, it was like the sun came out. My libido came back, as did my energy. I would recommend this to anyone with low testosterone and see what happens."

• Anc...
• July 8, 2013

Testosterone for Hypogonadism, Male "Fortesta was my first try with a hormonal treatment. My doc rocks and had a discount card. I was following the directions as my testosterone levels were not in the normal range of 400-900 mg/dL. Anyway, after the same depression, insomnia, overall weakness, and symptoms some described here, my mega blood work revealed that I was at 109 on the tes-scale. The only warning I would put forth is to watch the dosage. I experienced some 'fits of irritability' and then slight back pimples, etc. So I adjusted the dosage to half and lasted twice as long. It worked out well as I am of smaller stature at 5'6" and 142 lbs. Too much testosterone. Works well and dries quickly."

• ben...
• Taken for 6 months to 1 year
• January 16, 2014

For Hypogonadism, Male "I'm male, 27, 6' 255 lbs. Went into doctor with anxiety, clinical depression, sexual issues, and body composition changes. Original testosterone level 50. 200 mg every two weeks bumped me up to 500 total testosterone. Mentally felt better and body looking better, but still had bedroom troubles, so I'm now on 300 mg weekly and feel the best I have in a really long time. Total testosterone 800."

• Anonymous
• March 18, 2012

For Hypogonadism, Male "I'm 33 years old and have no reason to be low on energy and motivation. In addition, I had a slight depression and an inability to focus, like my head was in a fog. Went to my doctor to find out what was wrong. I wasn't on any other medications, I'm 5' 10" and 160 pounds and otherwise very healthy. The doctor told me to exercise more, which I did, but was so tired that I just couldn't do anything. Went back to the doctor, and he did a full blood workup. Testosterone was 206 (350 - 1100 was normal at my lab), and he gave me a 200 mg/ml injection. All symptoms were gone, and my sex life has never been better. I feel like a new man, I had no idea just how much of an effect my low T was having on my life. This is my first injection."

• unk...
• November 5, 2019

Testosterone for Hypogonadism, Male "Update from my Aug 6, 2018 review under the name unknown. This product still gets a 10, but need to share my experience as a cautionary warning. Be careful not to let your testosterone get too high while on this product. I ended up with my Free T and E2 way too high, causing severe depression and insomnia. I have since worked with my primary care doctor to lower my dose to only 2x pumps, which is giving me better lab numbers more in line for a guy of my age (around 40)... Also, the generic is much cheaper and just as good, probably because they are made by the same people."

• Anonymous
• January 10, 2012

Testosterone for Hypogonadism, Male "Been on Testim for around 3 weeks now. Have noticed slight changes in libido, but not much in the way of anything else. My T levels were on the floor, so it may take a couple of months to get them sorted out. I suspect I have had low testosterone levels for a while now, but it was only when things got tough and I felt down, depressed, and thoroughly miserable at the age of 48 that I decided to see a doctor. I suggested to the GP that it was an androgen problem, and she told me that 99 percent of guys who come in and tell her that don't actually have low T. I persuaded her to run the test, and it came back low, 144 I think. Did a confirmation level, then I was referred to an endocrine consultant. Hopefully, I'll feel much better soon."

• InG...
• October 24, 2022

For Hypogonadism, Male "Testosterone literally changed my life. I'm 24 years old, and my T was so low even at 24 years old. I was super depressed, had no interest in living, social anxiety through the roof, tried dozens of meds with no relief. I was overweight, and my voice was soft, not manly. I had low bone density, people would ask me what's wrong with my arms, and the list goes on and on. I am now on enanthate injections every 10 days, and it's a night-and-day difference. I always knew that my mental struggle was due to testosterone deficiency, it's real. People, please get your T checked if you suffer from what I wrote above, it could change your life too."

• fib...
• Taken for less than 1 month
• May 16, 2012

For Hypogonadism, Male "I am 53 years old, started having depression issues, and my wife told me I had the same symptoms she had before she went on hormone therapy. Had my testosterone checked, and sure enough, it was in the low range. I was about 280, which is the low end of normal, but for someone my age, too low. Doctor suggested injections to build it up in my system. First week, I felt a difference within an hour after the shot. I felt like myself again and realized I hadn't felt this way in years. By the 4th day, I started coming down, was told to get in the gym and work out, which I suppose released more of the testosterone, and felt better again. But by the 7th day, I started crashing. Just had my 2nd shot and feel great again."

• Wad...
• Taken for 1 to 6 months
• April 19, 2022

Testosterone for Hypogonadism, Male "I do not like Aveed at all. The shot is slow and painful, it has caused me to become very irritable and depressed, and it has caused severe back pain. It has not helped my T-level at all. I'm going back to the 2-week shot that raised my T-level and helped me feel better than I had in many years."

• Mnm...
• Taken for 6 months to 1 year
• May 25, 2021

Testosterone for Hypogonadism, Male "The fix for patches falling off is using an alcohol prep pad prior to placing the patch. Make sure the alcohol evaporates and then stick the patch on. It will never fall off after that. I am 43 and had a 190 level, and after 4 months of 4 mg patch and getting vitamin D pills, I am at 1070, which my Dr. is uncomfortable with. I am now on a 2 mg patch. This has changed my life. I had terrible depression, anxiety, panic, and no motivation. This all almost instantly lifted. I wasn't having issues with erections but do notice morning erections like I had when I was a teen. My body has lost its weird weight and I started finally building muscle. I have not been able to build muscle until now. My only complaint would be quality assurance. These patches are never the same. Too much glue causing aluminum disc to stay on patch when it should come off with cover. Some patches empty after 24 hrs, some don't seem to empty at all. Not sure what is up with that."

• SF ...
• Taken for 2 to 5 years
• June 11, 2016

Testosterone "I've been using this for a few years and have had a great experience. More energy, and I think it also helped with mild depression. About the odor-to me, it smells chemical and harsh when putting it on, but once it's on, I can't smell it. Some people don't smell it on me at all. Some people think it smells great on me. A lot of women who are candid enough to tell me really like it. The moral of the story is that the smell, as experienced by the person smelling it, is highly variable. Clearly, it has something to do with people's biochemical attractions. Note there are studies about women smelling men's worn clothing (without cologne or anything), and there's a wide variety of reactions and attraction."

• Anonymous
• November 8, 2009

Testosterone for Hypogonadism, Male "Testosterone was down to 88, felt depressed, no desire to do anything, just miserable. 5 days on 10 grams and feeling much better already!"

• Mar...
• Taken for 1 to 2 years
• July 11, 2022

Testosterone for Hypogonadism, Male "Week 2-4, I feel like I’m 18 again with a painful 24/7 erection. On week 5, it starts to level out, by week 8, I’m a tired, depressed, couch-ridden mess."