Silenor Alternatives Compared
Silenor | Trazodone | Ambien |
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Silenor (doxepin) | Trazodone | Ambien (zolpidem) |
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Prescription only
Prescribed for Insomnia. Silenor may also be used for purposes not listed in this medication guide. |
Prescription only
Trazodone is mostly used for its sleep-inducing effects (an off-label indication) rather than as an antidepressant. Only generic forms are available which makes it a lot cheaper than some other... View more |
Prescription only
Ambien induces sleep; however, Ambien CR, in particular, may impair physical and mental capabilities the next day. Ambien has also been associated with complex or dangerous sleep-related behaviors... View more |
Related suggestions Insomnia
Popular comparisons
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More about Silenor (doxepin) | More about Trazodone | More about Ambien (zolpidem) | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Silenor has an average rating of 6.3 out of 10 from a total of 127 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 37% reported a negative effect. |
Trazodone has an average rating of 6.3 out of 10 from a total of 1410 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. |
Ambien has an average rating of 7.0 out of 10 from a total of 562 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 21% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Silenor side effects in more detail. |
See also: trazodone side effects in more detail. |
See also: Ambien side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Silenor prices |
View all trazodone prices |
View all Ambien prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
Other doxepin brands include: Adapin |
N/A |
Other zolpidem brands include: Ambien CR, Edluar, Zolpimist | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
25 hours |
7.5 hours |
2.6 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 694 drugs are known to interact with Silenor:
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A total of 647 drugs are known to interact with trazodone:
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A total of 463 drugs are known to interact with Ambien:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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Disease Interactions | ||||||||||||||||||||||||||
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First Approval Date | ||||||||||||||||||||||||||
March 17, 2010 |
December 24, 1981 |
December 16, 1992 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.