Silenor Interactions
There are 704 drugs known to interact with Silenor (doxepin), along with 26 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 143 are major, 536 are moderate, and 25 are minor.
- View all 704 medications that may interact with Silenor
- View Silenor alcohol/food interactions (1)
- View Silenor disease interactions (26)
Most frequently checked interactions
View interaction reports for Silenor (doxepin) and the medicines listed below.
- alprazolam
- Ambien (zolpidem)
- amlodipine
- atorvastatin
- Belsomra (suvorexant)
- bupropion
- clonazepam
- cyclobenzaprine
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- gabapentin
- ibuprofen
- levothyroxine
- lisinopril
- Lyrica (pregabalin)
- melatonin
- metformin
- omeprazole
- oxycodone
- pantoprazole
- prednisone
- propranolol
- Synthroid (levothyroxine)
- tizanidine
- topiramate
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
Silenor alcohol/food interactions
There is 1 alcohol/food interaction with Silenor (doxepin).
Silenor disease interactions
There are 26 disease interactions with Silenor (doxepin) which include:
- depression
- anticholinergic effects
- anticholinergic effects
- cardiovascular disease
- pheochromocytoma
- acute myocardial infarction recovery
- cardiovascular disease
- seizure disorders
- glaucoma
- liver disease
- renal/liver disease
- bipolar screening
- bone marrow suppression
- diabetes
- renal/liver disease
- schizophrenia/bipolar disorder
- tardive dyskinesia
- acute alcohol intoxication
- bipolar disorder screening
- glaucoma
- hyper/hypoglycemia
- liver/renal disease
- neutropenia
- schizophrenia
- thyroid disorders
- urinary retention
More about Silenor (doxepin)
- Silenor consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (127)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Generic availability
- FDA approval history
- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
Ativan
Ativan is a benzodiazepine used to treat anxiety disorders or anxiety associated with depression ...
Benadryl
Benadryl is an antihistamine and is used to treat sneezing, runny nose, itching and other ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Ambien
Ambien (zolpidem) is a prescription sedative used to treat insomnia, helping you fall asleep and ...
Lunesta
Lunesta is a sedative and is used to treat insomnia. Lunesta's effects typically begin within 30 ...
Eszopiclone
Eszopiclone (brand name Lunesta) is a sedative and is used to treat insomnia. Eszopiclone's effects ...
Temazepam
Temazepam is used to treat insomnia (trouble sleeping). Learn about side effects, interactions and ...
Diphenhydramine
Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Zolpidem
Zolpidem is a sedative-hypnotic medicine used for the short-term treatment of insomnia (trouble ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.