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Silenor and Depression: What Users Say

Depression: mentioned by 7 users (5.5%)

Based on user experiences from 127 Silenor reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

drowsiness 8.7%
anxiety 6.3%
depression 5.5%
headaches 3.9%
nightmares 3.9%
hallucinations 3.1%
hangover 3.1%
irritability 3.1%
tiredness 3.1%
vivid dreams 3.1%

Reviews for Silenor

Commonly mentioned side effects
  • blh...
  • May 25, 2017

For Insomnia "I was prescribed 3 mg tablets for insomnia. The first night, I took one about 45 minutes before bedtime and did not find it helped me sleep at all. However, I was extremely groggy the next morning and ended up back in bed shortly after lunch, sleeping for almost 2 hours. I tried it two more times, taking it earlier each time, but the effect was the same: it takes too long to work and leaves me groggy and unable to function the next day. I will not be taking it anymore."

1 / 10
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86 Report
  • M H...
  • Taken for 6 months to 1 year
  • September 17, 2017

For Insomnia "Used to take Ambien, but side effects were starting to drive me nuts. Nightmares, almost depressed when waking up. Silenor really saved me. Incredible feeling, like normal sleep. No side effects at all in my case. I'm surprised it's not more promoted."

10 / 10
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83 Report
  • Ins...
  • September 4, 2016

For Insomnia "Silenor literally saved my life! Before a month ago, I never had sleeping issues, but after recently moving in with my boyfriend in an apartment with neighbors' dogs that kept me up all night, there was a 2-week period where I literally didn't sleep at all. I was starting to feel extremely anxious, depressed, and as if I was losing all control of my life. Silenor is non-addictive, which made me feel more comfortable about taking it. I still woke up in the night some nights, but it put me to sleep no problem. It allowed me to get back on track with my sleep and daily routines."

9 / 10
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45 Report

Frequently asked questions

  • GDa...
  • May 28, 2018

For Insomnia "I was prescribed Silenor for insomnia, which I battled with for 3 years. I was taking a high dose of Melatonin to sleep, but that stopped working when I was going through a stressful period. Took 3 mg of Silenor the first night. Although I slept 5-6 hours, I felt horrible the next day. I felt like crying all day. I increased the dose to 4.5 mg and was able to get 7 hours of sleep, but the negative mood became more prominent during the day. I was depressed and miserable. I stuck with it for 2 weeks, but my mood was getting worse. I couldn't keep on taking it. I don't know if these are only initial side effects that will go away after a month or so, but I personally could not handle the depressive symptoms (major) it gave me, so I decided to stop it after 2 weeks only. I felt better immediately, even though I am still struggling with sleep... I have to see my doctor and try Trazodone."

2 / 10
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33 Report
  • GDa...
  • May 28, 2018

For Insomnia "I was prescribed Silenor for insomnia, which I battled with for 3 years. I was taking a high dose of Melatonin to sleep, but that stopped working when I was going through a stressful period. Took 3 mg of Silenor the first night. Although I slept 5-6 hours, I felt horrible the next day. I felt like crying all day. I increased the dose to 4.5 mg and was able to get 7 hours of sleep, but the negative mood became more prominent during the day. I was depressed and miserable. I stuck with it for 2 weeks, but my mood was getting worse. I couldn't keep on taking it. I don't know if these are only initial side effects that will go away after a month or so, but I personally could not handle the depressive symptoms (major) it gave me, so I decided to stop it after 2 weeks only. I felt better immediately, even though I am still struggling with sleep... I have to see my doctor and try Trazodone."

2 / 10
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33 Report

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  • Anonymous
  • August 18, 2011

For Insomnia "I use Silenor only 2 times a week, I alternate it with Ambien. Silenor allows me to sleep the full 7-8 hours but leaves me useless the next day. So I take it when I don't have to work the next day. But oh, I love the sleep I get with Silenor! Ambien allows me to fall asleep and sporadically allows me to stay asleep."

9 / 10
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31 Report
  • Anonymous
  • Taken for less than 1 month
  • June 22, 2018

For Insomnia "Worst drug ever. Brain fog for days after. Sent me into deep depression from one dose. Extremely expensive for a very old drug. NEVER AGAIN."

1 / 10
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32 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.