Comparing Risperidone vs Zyprexa
Risperidone Remove Risperidone from your drug comparison | Zyprexa Remove Zyprexa from your drug comparison |
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Risperidone Remove Risperidone from your drug comparison | Zyprexa olanzapine Remove Zyprexa from your drug comparison | ||||||||||||||||
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Risperidone is an antipsychotic that relieves psychotic symptoms in people with schizophrenia or mania and is also used in the treatment of autistic disorder. Side effects are less likely at lower... View more |
Zyprexa is an antipsychotic used in the treatment of schizophrenia and bipolar disorders. Weight gain associated with Zyprexa is common. Prescribed for Bipolar Disorder, Schizophrenia, Major... View more |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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5.6
For Bipolar Disorder: I have been on this medication for about a month now. It has greatly helped with my paranoia and irritability. There are a few bad things though. It has caused my bladder to go by itself if I do not go as soon as possible and also my thought at times is a little slow. I have not noticed any weight gain and the bad that comes with it can make life a little difficult. It is the only medicine that has even remotely helped with my manic symptoms. |
6.2
For Bipolar Disorder: This medicine works really well as a mood stabilizer for me. The only MAJOR drawback is weight gain. I just can't control myself when the carb cravings happen. I am usually very much in control of my dietary habits, but on Zyprexa that just isn't possible. I also suffer from schizoaffective disorder and hear voices. Although Zyprexa suppresses them, it does not completely get rid of them in my case; they are quiet enough to tolerate though. I have gained 35 pounds in less than about a month and a half. I am going to wean off of these and ask the psych-doc for something else. For Bipolar Disorder: First year on 5mg at night helped my mood, anger outbursts and anxiety a great deal. Did develop high cholesterol and gained 15 pounds, but the trade off was worth it. Also helps wonderfully with insomnia. After the year mark it was no longer handling my anger well. Started having 2-3 inappropriate outbursts a week. Pdoc started me on geodon but couldn't handle the side effects, so back to the zyprexa I went with another 2.5mg added in the morning and gained another 6 pounds. Have tried other AAPs but can't handle the side effects so I'm still on the zyprexa for now until I get brave enough to try something else again. Taking with Pristiq, Trileptal, Vistiril and Xanax. |
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Drug Class |
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Side Effects |
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Commonly reported side effects include: agitation, akathisia, anxiety, constipation, dizziness, drowsiness, dystonia, extrapyramidal reaction, nausea, rhinitis, and weight gain. See the full risperidone side effects document. |
Common side effects include: asthenia, dizziness, drowsiness, extrapyramidal reaction, hyperkinetic muscle activity, akinesia, cogwheel rigidity, drug-induced parkinson's disease, dyspepsia, mask-like face, and xerostomia. See the full Zyprexa side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all risperidone prices |
View all Zyprexa prices and generic prices |
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Generic Availability |
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Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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Perseris, Risperdal, Risperdal Consta | Other olanzapine brands include: Zyprexa Intramuscular, Zyprexa Relprevv, Zyprexa Zydis | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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24 hours |
54 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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FDA Alerts |
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Drug Interactions |
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A total of 622 drugs are known to interact with risperidone:
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A total of 597 drugs are known to interact with Zyprexa:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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December 29, 1993 |
September 30, 1996 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Bipolar Disorder: I have Bi-Polar II and I have been taking 0.5 mg 1x a day of Risperidone. It has calmed my irritability and my thinking seems more organized. I definitely noticed an immediate difference. It addressed not mood as much as thinking and perception. For mood, I take Lamictal and started taking Topamax also JUST to combat the weight gain from the Risperidone. The weight gain is miserable and THAT depresses me. (I was originally on Lithium but that affected my thyroid adversely and although it had a good effect otherwise, it also "flattened out" my mood to such an extent that I felt really blah).