Comparing Clozapine vs Risperidone
Clozapine Remove Clozapine from your drug comparison | Risperidone Remove Risperidone from your drug comparison |
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Clozapine Remove Clozapine from your drug comparison | Risperidone Remove Risperidone from your drug comparison | ||||||||||||||||
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Prescribed for Schizophrenia. May also be prescribed off label for Borderline Personality Disorder, Paranoid Disorder. |
Risperidone is an antipsychotic that relieves psychotic symptoms in people with schizophrenia or mania and is also used in the treatment of autistic disorder. Side effects are less likely at lower... View more |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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7.6
For Schizophrenia: My son starting showing signs of psychosis right after his 14th bday. Diagnosed with schizophrenia 6 months later. He was in a constant state of his own reality and heard voices on a regular basis. Seroqel, Zyprexa, Invega, and Ability did nothing for him. His psychiatrist prescribed Clozapine as a last resort. I won't allow his dosage any higher than 300mg per day for now since the side effects worry me. This drug has been a lifesaver to allow him to participate in the regular world and quiet the voices where he can focus on real ppl. It makes him drowsy so he takes it at night. Weight gain is significant but most antipsychotics will do this. Regular blood monitoring to make sure his WBC stays normal. So good, so far. |
5.6
For Bipolar Disorder: I have Bi-Polar II and I have been taking 0.5 mg 1x a day of Risperidone. It has calmed my irritability and my thinking seems more organized. I definitely noticed an immediate difference. It addressed not mood as much as thinking and perception. For mood, I take Lamictal and started taking Topamax also JUST to combat the weight gain from the Risperidone. The weight gain is miserable and THAT depresses me. (I was originally on Lithium but that affected my thyroid adversely and although it had a good effect otherwise, it also "flattened out" my mood to such an extent that I felt really blah). For Bipolar Disorder: I have been on this medication for about a month now. It has greatly helped with my paranoia and irritability. There are a few bad things though. It has caused my bladder to go by itself if I do not go as soon as possible and also my thought at times is a little slow. I have not noticed any weight gain and the bad that comes with it can make life a little difficult. It is the only medicine that has even remotely helped with my manic symptoms. |
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Drug Class |
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Side Effects |
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Commonly reported side effects include: hypotension, fever, tachycardia, constipation, dizziness, headache, nausea, sedated state, vomiting, and weight gain. See the full clozapine side effects document. |
Commonly reported side effects include: agitation, akathisia, anxiety, constipation, dizziness, drowsiness, dystonia, extrapyramidal reaction, nausea, rhinitis, and weight gain. See the full risperidone side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all clozapine prices |
View all risperidone prices |
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Generic Availability |
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Yes (this medicine) |
Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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Clopine, Clozapine Synthon, Clozaril, Denzapine, FazaClo, Versacloz | Perseris, Risperdal, Risperdal Consta | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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10.3 hours |
24 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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FDA Alerts |
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Drug Interactions |
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A total of 819 drugs are known to interact with clozapine:
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A total of 622 drugs are known to interact with risperidone:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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September 26, 1989 |
December 29, 1993 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Schizophrenia: My son is in his early 20'and has schitsoaffective dissorder.He has been on at least five different medications for his illness. And nothing seem to help or if it did it lasted only for a little while or he had severe allergic reactions. So he started clozapine/clozaril around a month ago. And it has made a big difference .The voices gradually are going away. He can actually sit and watch TV and have a conversation. He is enjoying things again. We do go for blood work every week which he does not mind. This medicine is working and I'm hoping his blood work comes back good every week, Because to see him getting better is such a relief . And I am hopeful for a happy productive life for him. Things are looking up.